目的 探讨KDQ量表的信度与效度。方法 方便取样，选取2007年12月～2008年4月在北京大学人民医院血液净化中心进行维持性血液透析的患者共100例。采用自设问卷，问卷主要包括三部分：①一般资料；②SF-36量表；③KDQ量表。计算KDQ量表的信度和效度。 结果 KDQ量表重测信度系数为0.706；分半信度 R=0.821；内部一致性信度的Cronbach,sа系数，除躯体症状的Cronbach,sа值偏低外，其它纬度а值在0.508～0.852之间，显示出较好的内部一致性； 量表有较好的结构效度和效标效度。 结论 KDQ量表在血液透析患者中有良好的信度与效度，适用于血液透析患者的测量。

Objective To explore the reliability and validity of Kidney Disease Questionnaire (KDQ) on measuring life quality in patients on maintenance hemodialysis. Method Convenient sampling was used. A total of 100 patients on maintenance hemodialysis from the Hemodialysis Center of People’s Hospital were tested. The self-designed questionnaire includes three parts, namely the demographical data, SF-36 short form, and KDQ. Data regarding life quality of the patients were calculated to assess the reliability and validity of KDQ. Results The test-retest reliability of KDQ was 0.706, and the split-half reliability was 0.821. Except for the subscale of physical symptoms, Cronbach’s a coefficient of subscales ranged from 0.508～0.852. The questionnaire also showed good construction validity and criterion-related validity. Conclusion KDQ can be served as a proper scale to measure life quality in patients on hemodialysis.