中国血液净化

›› 2010, Vol. 9 ›› Issue (5): 255-257.

• 临床研究 • 上一篇    下一篇

老年维持性血液透析患者骨密度的测定结果与分析

李全瑞 张 沛 贾 强   

  1. 首都医科大学宣武医院1感染科，2肾脏内科
  • 收稿日期:2010-03-02 修回日期:1900-01-01 出版日期:2010-05-12 发布日期:2010-05-12

The analysis about the results of bone density in elderly patients on maintenance hemodialysis

LI Quan-rui, ZHANG Pei, JIA Qiang   

  1. Department of 1Infection. 2Kndney,Beijing Xuanwu Hospital,Capital University of Medical Science,Beijing (100053),China
  • Received:2010-03-02 Revised:1900-01-01 Online:2010-05-12 Published:2010-05-12

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摘要：

【摘要】目的 对老年维持性血液透析患者(MHD)骨密度情况进行测定研究，了解骨质疏松患病情况。方法 选择首都医科大学宣武医院肾内科血液净化中心56例老年维持性血液透析患者作为试验组，52例中青年维持性血液透析患者及43例老年终末期尿毒症非透析患者分别作为对照组。记录患者的年龄、性别、身高、体重、骨折等资料。采用双能X线骨密度仪测量所有样本的腰椎(L1～L4)及股骨骨密度等指标。用SPSS软件进行统计学分析。结果 骨质疏松总患病率、股骨骨质疏松患病率老年透析组分别高于老年非透析组和中青年透析组(P＜0.05)；腰椎骨质疏松患病率相比无显著性差异(P＞0.05)，而老年透析组女性腰椎骨质疏松患病率高于老年男性,有显著性差异(P＜0.05)。 结论 老年MHD患者与其他人群相比骨密度下降以皮质骨为明显，骨质疏松患病率高，患病情况更严重且更易发生骨折，应给予针对性治疗。

关键词: 血液透析, 骨密度, 骨质疏松, 老年

Abstract:

【Abstract】Objective To explored the bone mineral loss or osteoporosis in elderly population on maintenance hemodialysis (MHD). Methods 56 aged patients on MHD in the blood purification center of Nephrology department of Xuanwu Hospital Capital Medical University were recruited as test group, 52 young patients on MHD and 43 elderly patients with dialysis-independent end stage renal disease (ESRD) were selected as control groups. The patients age, sex, height, body weight, bone fracture events, and so on were recorded. Mineral density of spinal bone (L1～L4) and femoral bone were measured by dual energy X ray absorptiometry. SPSS software was used for statistical analysis. Results The frequency of femoral osteoporosis in elderly dialysis group was higher than those in non-dialysis aged group and the young dialysis group (P<0.05), while there were no significant differences in frequency of lumbar osteoporosis across groups (P＞0.05).The old women of lumbar osteoporosis in elderly men with high significant difference (P<0.05).Conclusion Elderly patients on maintenance hemodialysis are more likely to suffer from femoral osteoporosis

Key words: osteoporosis