Objective: to investigate the application effect of quality control circle (QCC) activity in reducing complications of arteriovenous fistula puncture .Methods: Established QCC activity groups, selected "Reducing arteriovenous fistula puncture complications" as the theme, to survey the times of complications in 10000 times arteriovenous fistula puncture operation in dialysis patients from February 1, 2014 to March 31,2014 in our blood purification department. We set the target , analyze causes of complication , finally , take measures to improve. Results: through this improvement, the incidence of complications of arteriovenous fistula puncture per ten thousand decline from (540/10000) 5.4% to (230/10000) 2.3%. Compared to before QCC, retreat pin times (166 vs 61), inferior blood flow times (128 vs 48), bleeding times (135 vs47) after QCC show significant difference (P<0.05).Circle members show significant improvements in teamwork, communication skills, professional competence, responsibility, problem-solving skills, self-confidence , ability to use quality control circles and work enthusiasm. Conclusion: QCC can not only reduce incidence of complications of arteriovenous fistula puncture, but also improve the management level of QCC members and individual overall quality.