中国血液净化

›› 2004, Vol. 3 ›› Issue (1): 15-17.

• 论著 • 上一篇    下一篇

糖尿病与非糖尿病腹膜透析患者容量负荷状况比较

甘红兵 陈孟华 汪 涛   

  1. 100034 北京,北京大学第一医院肾内科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2004-01-19 发布日期:2004-01-19

  • Received:1900-01-01 Revised:1900-01-01 Online:2004-01-19 Published:2004-01-19

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摘要： 目的 比较糖尿病与非糖尿病腹膜透析患者容量负荷状况。方法 采用横断面研究方法调查了所有接受腹膜透析治疗至少3个月以上的患者容量负荷状况，分析容量负荷与24小时超滤量、尿量等的关系。结果 2002年5月至7月间共58例腹膜透析患者，其中糖尿病终末期肾病( DNESRD) 20例；非糖尿病终末期肾病 (NDNESRD) 38例。两组患者年龄、身高、性别分布以及尿量比较差异均无显著性（P＞0.05）；DNESRD 组体重、透析液糖浓度、糖总量、透析液总量、超滤量及总清除量均大于NDNESRD 组，统计学检验差异均有显著性。DNESRD 组水肿程度较NDNESRD 组严重，差异有显著性（P＜0.01）。结论 DNESRD 与NDNESRD两组患者均存在容量超负荷状况，DNESRD组尤为严重。腹膜透析患者应严格限制水盐的摄入，维持良好的水平衡。

关键词: 糖尿病, 腹膜透析, 容量负荷

Abstract:

Objective To compare the fluid status in diabetic and non-diabetic peritoneal dialysis patients. Methods In a cross-sectional study, 58 patients treated with peritoneal dialysis for at least 3 months were investigated. Among them, 20 cases were diabetics and the other cases were nondiabetics. We reviewed their dialysis prescription, peritoneal ultrafiltration, urine volume and fluid status. Results There were no significant differences in the age，gender, height and urine volume between the two groups. However, the body weights, dialysate doses, dialysate glucose load, peritoneal ultrafiltration and total fluid removal were significantly higher in diabetics as compared to non-diabetics. Furthermore, there were significantly more edematous patients in diabetics as compared to non-diabetics. Conclusions The present study suggest that our diabetic patients were more fluid overloaded as compared to non-diabetics despite that they used more hypertonic glucose solutions and had higher peritoneal ultrafiltration and higher total fluid removal; this indicates that our diabetic patients must have significantly higher salt and fluid intake. 

Key words: Peritoneal dialysis, Fluid status

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