中国血液净化

›› 2004, Vol. 3 ›› Issue (7): 385-387.

• 人工肝 • 上一篇    下一篇

人工肝血浆置换治疗重型肝炎临床观察 

柳忠生 单忠元 李亚明 周 汉 姬淑芳 金淑艳 韩白乙拉 赵桂兰 吴晓明   

  1. 028000 通辽，内蒙古通辽市传染病医院(柳忠生，单忠元，周汉，姬淑芳，金淑艳，韩白乙拉，赵桂兰，吴晓明)100054 北京，首都医科大学附属北京佑安医院人工肝中心(李亚明)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2004-07-12 发布日期:2004-07-12

  • Received:1900-01-01 Revised:1900-01-01 Online:2004-07-12 Published:2004-07-12

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摘要：

目的 探讨人工肝血浆置换治疗重型肝炎的疗效及影响疗效的主要因素。方法 将92例重型肝炎患者随机分为人工肝治疗组与对照组，两组内科基础治疗相似。其中52例人工肝治疗组患者加用血浆置换治疗共85例次，对照组仅接受内科基础治疗。通过观察两组患者治疗前后临床症状、生化指标等的变化，判断人工肝血浆置换的疗效。结果 治疗组患者经血浆置换后，临床症状都得到一定程度的改善，肝功能明显好转，总有效率61.53% ，其中早期重型肝炎有效率为80%，中期69.23%，与对照组相比均有非常显著性差异（P<0.01）。结论 血浆置换治疗重型肝炎疗效肯定，掌握治疗时机是提高疗效的关键。另外，血浆置换亦可作为判断预后的手段。

关键词: 人工肝, 血浆置换, 重型肝炎

Abstract:

Objective To observe the therapeutic effects of plasma exchange for patients suffered from gravis hepatitis, and analyze the main factors which influence the results. Methods Ninety-two patients with severe hepatitis were divided into two groups randomly: the treatment group and control group. In the treatment group, the patients were treated with the plasma exchange on the basis of routine medical therapy, but the control group received the routine medical therapy only. The signs such as main symptoms, several blood biochemical data before and after treatment were observed and analyzed for judging the effects. Results The patients' symptoms and liver functions with plasma exchange improved obviously, and the total effective rate was 61.53%. There were significant differences between the two groups for early and middle stage cases. Conclusion Plasma exchange is an effective method for gravis hepatitis, and it may also be used to judge prognosis.

Key words: Plasma exchange, Severe hepatitis

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