中国血液净化

›› 2009, Vol. 8 ›› Issue (11): 615-617.

• 论著 • 上一篇    下一篇

乙型病毒性肝炎核心抗体阳性对肾移植患者影响的临床研究

穆星宇 秦 燕 范 昱 张 芳 王 忠   

  1. 上海市交通大学附属第一人民医院肾移植科
  • 收稿日期:2009-07-21 修回日期:1900-01-01 出版日期:2009-11-12 发布日期:2009-11-12

The influence of anti-HBc antibody on patients after renal transplantation

MU Xing-yu, QIN Yan, FAN Yu, ZHANG Fang, WANG Zhong   

  1. Department of Renal Transplantation, Shanghai Jiaotong University Affiliated First People’s Hospital
  • Received:2009-07-21 Revised:1900-01-01 Online:2009-11-12 Published:2009-11-12

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摘要：

【摘要】目的 探讨乙肝核心抗体对于肾移植患者的影响。方法 观察不同乙肝标志物[A组(HBsAg+，HBcAb+)，B组(HBsAg-，HBcAb+),C组(HBsAg-，HBcAb-)]组间肾移植患者肝功能、肾功能等指标间的差异。 结果 A组肝功能异常发生率52.0%，B组肝功能异常发生率36.8%，C组肝功能异常发生率8.69%，三组间比较均有显著差异。 结论 肾移植患者合并单纯乙肝核心抗体阳性肝功能异常发生率仍较高.

关键词: 肾移植, 肝功能异常, 乙肝病毒

Abstract:

【Abstract】 Objective To study the influence of anti-hepatitis B core antigen antibody (HBcAb) on renal transplantation patients. Methods Patients were divided into 3 groups based on the markers for hepatitis B virus infection: Group A (HBsAg+ and HBcAb+), Group B (HBsAg- and HBcAb+), and Group C (HBsAg- and HBcAb-). Liver damage and kidney function were analyzed among the 3 groups after renal transplantation. Results The incidence of liver damage was 52.0% in group A, 36.8% in group B, and 8.69% in group C. Significant differences were found among the 3 groups. Conclusions Liver damage is frequently seen in patients with positive HBcAb after transplantation.

Key words: Liver damage, Hepatitis B virus