维持性血液透析患者睡眠质量、抑郁和生活质量相关 关系的研究

›› 2009, Vol. 8 ›› Issue (9): 508-511.

维持性血液透析患者睡眠质量、抑郁和生活质量相关关系的研究

张俊王成汤颖娄探奇

中山大学附属第三医院肾内科; 中山大学附属第二医院肾内科; 中山大学附属第三医院肾内科

收稿日期:2009-03-19 修回日期:1900-01-01 出版日期:2009-09-12 发布日期:2009-09-12

Correlation study among sleep quality, depression and life quality in maintenance hemodialysis patients

ZHANG Jun, WANG Chen, TANG Ying, LOU Tan-Qi

1Department of Nephrology, The Third Affiliated Hospital (510630); 2Department of Nephrology, The Second Affiliated Hospital (510120), Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou, China

Received:2009-03-19 Revised:1900-01-01 Online:2009-09-12 Published:2009-09-12

摘要/Abstract

摘要：

【摘要】目的探讨维持性血液透析患者睡眠质量、抑郁与生活质量之间的关系。方法收集符合标准维持性血液透析患者71例，采用匹兹堡睡眠质量指数(PSQI)评估睡眠质量，以简明健康状况调查表(SF-36 量表)和BECK抑郁自评问卷(BDI)分别评估生活质量和抑郁情况。记录年龄、性别、婚姻、干体重、血红蛋白、铁蛋白、转铁蛋白饱和度、钙、磷、全段甲状旁腺激素、白蛋白、C-反应蛋白、透前及透后血肌酐、尿素氮。结果睡眠质量较差(PSQI评分＞5)的血液透析患者占76.1%；睡眠质量较好组患者的生活质量总分、生理及心理健康总分均高于睡眠质量较差组(P＜0.01)，睡眠质量较差组的抑郁评分及年龄高于睡眠质量较好组(P＜0.05)；中-重度抑郁患者（BDI评分≥8分）占63.4%，该组患者生活质量总分、生理及心理健康总分均低于非中-重度抑郁组(P＜0.01)，且睡眠质量差(P＜0.01)；SF-36生活质量总分、生理健康总分及心理健康总分和睡眠质量及抑郁相关(P＜0.01)，睡眠质量和抑郁是生活质量独立的危险因素。结论维持性血液透析患者睡眠质量较差、抑郁较为常见，睡眠和抑郁之间相互影响，并且降低了患者的生活质量。

关键词: 维持性血液透析, 生活质量, 睡眠质量, 抑郁

Abstract:

【Abstract】 Objective to explore the correlation among sleep quality, depression and life quality in maintenance hemodialysis (MHD) patients. Methods Seventy-one patients fitting the criteria of MHD were recruited in this study. Subjective sleep quality was assessed by the Pittsburgh Sleep Quality Index (PSQI). Life quality and depression condition were evaluated by SF-36 and Beck Depression Inventory (BDI), respectively. Patients’ age, gender, marital status, dry weight, blood hemoglobin, and serum ferritin, transferring saturation, calcium, phosphorus, intact parathyroid hormone, albumin, C-reactive protein, creatinine and urea nitrogen were collected before and after dialysis. Results Poor sleep quality as defined by PSQI＞5 was found in 76.1% MHD patients. Patients with poor sleep quality had lower SF-36 scores, physical component summary score (PCS) and mental component summary score (MCS) (P＜0.01), as well as higher BDI score and older age (P＜0.05). Moderate to severe depressive symptoms as defined by BDI ≥ 8 were found in 63.4% MHD patients. Patients with moderate to severe depression also had lower SF-36 scores, PCS and MCS (P＜0.01), and higher PSQI score, as compared with those in patients without moderate to severe depression (P＜0.01). SF-36 score, PCS and MCS were closely related with PSQI score and BDI score (P＜0.01). Depression and sleep quality were the independent risk factors for life quality. Conclusion Our MHD patients had poor sleep quality and a high prevalence of depressive symptoms, which influenced each other and led to poor life quality.

Key words: Life quality, Sleep quality, Depression

张俊王成汤颖娄探奇. 维持性血液透析患者睡眠质量、抑郁和生活质量相关关系的研究[J]. , 2009, 8(9): 508-511.

ZHANG Jun;WANG Chen;TANG Ying;LOU Tan-Qi. Correlation study among sleep quality, depression and life quality in maintenance hemodialysis patients[J]. , 2009, 8(9): 508-511.