Abstract: Abdominal aorta saddle embolism (ASE) has high mortality,amputation rate. Emergency operate is the only way to save lives. However , because of the ischemia-reperfusion injury , suffers can not only lose the blood flow , but also aggravate the primary ischemia tissues, even develop to multiple organ dysfunction syndrome(MODS). Continuous blood purification (CBP) or continuous renal replacement therapy (CRRT) can continuous and slowly remove water and solute, becoming an efficiency and important treatment method. It has been widely used in critical illness such as acute renal failure,sepsis,severe acute pancreatitis. This article elaborate the therapeutic mechanism of continuous blood purification in ASE and introduce the specific application including therapy time and model.