中国血液净化

中国血液净化 ›› 2013, Vol. 12 ›› Issue (09): 483-486.doi: 10.3969/j.issn.1671-4091.2013.09.00

• 临床研究 • 上一篇    下一篇

贝前列素钠对提高老年患者动静脉内瘘术成功率的观察

肖胜,胡诗德,简讯,马懿,杨乔岚,曾蜀春   

  1. 川北医学院附属第二医院（四川绵阳四0四医院）
  • 收稿日期:2013-03-14 修回日期:2013-07-02 出版日期:2013-09-12 发布日期:2013-09-12
  • 通讯作者: 简讯 xun_jian404@sina.com E-mail:xun_jian404@sina.com

Beraprost sodium in elderly patients with uremia arteriovenous fistula Applied Research

  • Received:2013-03-14 Revised:2013-07-02 Online:2013-09-12 Published:2013-09-12

RichHTML

0

PDF

204

摘要： 目的：观察贝前列素钠对老年患者动静脉内瘘的作用与效果。方法：本研究纳入82例老年患者行动静脉内瘘术患者，随机分为贝前列素钠治疗组42例，对照组40例，对两组动静脉内瘘术成功率、并发症发生率、内瘘术后血管及血流变化情况、血常规及凝血分析变化、药物不良反应进行临床观察和比较。结果：治疗组动静脉内瘘术后2周及4周成功率（97.6% 、97.6%）比对照组高，差异有统计学意义（x2=12.48 P=0.002；x2=11.72 P=0.014），治疗组术后并发症发生率（4.8%）比对照组术后并发症发生率（55%）低，差异有统计学意义（x2=21.45 P=0.012），内瘘术后四周血流量（406.4±108.4）与对照组术后四周血流量（228.20±88.6）比较，差异有统计学意义（F=246.238，P=0.000），比较治疗组术前及术后血常规及凝血分析比较，差异无统计学意义（P>0.05）。结论：贝前列素钠能够提高老年患者动静脉内瘘术的成功率，且疗效确切。

关键词: 贝前列素钠, 老年患者, 动静脉内瘘术, 成功率, 观察

Abstract: Objective Observation of beraprost sodium on elderly patients action and effect of arteriovenous fistula .Methods The study included 82 elderly patients action venous fistula surgery were randomly divided into the beraprost sodium therapy group (n = 42), control group (n = 40) , the success rate of the two groups of arteriovenous fistula , the incidence of complications, fistula after the blood vessels and blood flow changes , blood and coagulation analyzer change, adverse drug reactions , clinical observation and comparison.Results Treatment of arteriovenous fistula after 2 weeks and 4 weeks of success rate (97.6%, 97.6%) higher than in the control group, the difference was statistically significant (x2=12.48 P=0.002; x2=11.72 P=0.014), the treatment group the incidence of postoperative complications (4.8%) than in the control group the incidence of postoperative complications (55%), the difference is statistically significance (x2=21.45 P=0.012), fistula postoperative around blood flow (406.4 ± 106.4) and the control group after around blood flow (228.20 ± 88.6), the difference was statistically significant (F=246.238, P=0.000), the treatment group before and after the blood and the blood coagulation analysis comparison, no significant difference (P>0.05).Conclusion Beraprost sodium can improve the intemal arteriovenous fistula operation success rate in elderly patients and curative effect.

Key words: Beraprost sodium, Elderly patients, Arteriovenous fistula, Success rate, Observation