中国血液净化

中国血液净化 ›› 2013, Vol. 12 ›› Issue (09): 491-495.doi: 10.3969/j.issn.1671-4091.2013.09.00

• 临床研究 • 上一篇    下一篇

德阳地区维持性血液透析患者生存质量及其影响因素的多中心研究

宋斌1,李海燕1,李隽1,李培贵2,张洪福3,陈长云4,高辉5,孙宏6   

  1. 1. 德阳市人民医院
    2. 广汉市第二人民医院
    3. 什邡市人民医院
    4. 绵竹市人民医院
    5. 中江县人民医院
    6. 什邡市中医院
  • 收稿日期:2013-03-25 修回日期:2013-06-21 出版日期:2013-09-12 发布日期:2013-09-12
  • 通讯作者: 宋斌 E-mail:sb8052@126.com

Multi-center investigation of life quality and its influence factors in patients with maintenance hemodialysis in the Deyang area

  • Received:2013-03-25 Revised:2013-06-21 Online:2013-09-12 Published:2013-09-12

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摘要： 目的：了解德阳地区维持性血液透析（MHD）患者的生存质量现状及其影响因素，为提高透析患者生存质量提供依据。方法：采用多中心问卷调查的方法，选取德阳地区六家血液净化中心253名MHD患者作为调查对象，调查内容包括患者一般情况和临床资料，并采用终末期肾脏疾病透析患者调查表(kidney disease quality of life short form, KDQOL -SFTM)对其进行生存质量问卷调查，评分结果分别与国内北京郊区、广州地区研究结果比较，同时采用Stepwise多元逐步回归分析影响德阳地区MHD患者生存质量的重要因素。结果：①德阳地区MHD患者在整体健康、生理功能、生理职能、情感职能、精力、症状与不适及医护鼓励方面得分高于北京郊区MHD患者，而在认知功能、社交质量、性功能、工作状态及患者满意度方面得分则低于北京郊区MHD患者，差异有统计学意义（P<0.05）；②德阳地区MHD患者在肾病负担、睡眠、社会支持、医护鼓励、患者满意度领域得分高于广州地区MHD患者，而在社会功能、生理职能、情感职能、疼痛、精力、认知功能、社交质量及工作状态方面得分则低于广州地区MHD患者，差异有统计学意义（P<0.05）；③Stepwise多元逐步回归分析结果显示，需要家属陪护透析、经历5.12大地震与整体健康方面得分呈负相关，男性患者在整体健康方面得分高于女性患者。结论：德阳地区MHD患者的生存质量总体水平低于广州地区；德阳地区MHD患者在部分生存质量调查领域得分高于北京郊区及广州地区MHD患者；需要家属陪护透析、经历5.12大地震与整体健康方面得分呈负相关，男性患者在整体健康方面得分高于女性患者。

关键词: 生存质量, 血液透析, 多中心研究

Abstract: Purpose: To evaluate the quality of life (QoL) of maintenance hemodialysis (MHD) patients in Deyang area, as well as analysis which factor impact on QoL of MHD patients. Method: To adopt the method of multicenter questionnaire survey, 253 MHD patients coming from six blood purification centers in Deyang area were included. The survey investigated the general conditions and clinical data of the patients. QoL were investigated by using KDQOL-SFTM questionnaire. The research results were compared with the results in Beijing suburb and Guangzhou area, meanwhile, Stepwise multiple regression analysis was adopted to analyze the important factors that influence the QoL of MHD patients in Deyang area. Result: 1. The scores of MHD patients in Deyang Area are higher than MHD patients in Beijing suburb on Overall health, Physical functioning, Role limitations- physical, Role limitations- emotional, energy,symptom/problem list and Dialysis staff encouragement, while their scores were lower than MHD patients in Beijing suburb on Cognitive function, Quality of social interaction, Sexual function ,Working status and Patient satisfaction, the differences were statistically significant（P<0.05）;2. The scores of MHD patients in Deyang Area were higher than MHD patients in Guangzhou Area on Burden of kidney disease, Sleep, Social support, Dialysis staff encouragement and Patient satisfaction, while their scores were lower than MHD patients in Guangzhou Area on Social function, Role limitations- physical, Role limitations- emotional, Pain, Energy, Cognitive function, Quality of social interaction and Working status, the differences were statistically significant（P<0.05）; 3. The results of Stepwise multiple regression analysis indicated a negative correlation between the need for family members to accompany, the experience of 5.12 earthquake and scores on the Overall health. The scores of male patients on Overall health were higher than that of female patients.Conclusion: The QoL of MHD patients in Deyang Area was generally lower than the Guangzhou Area. The scores of MHD patients in Deyang Area on some fields of QoL were higher than MHD patients in Beijing suburb and Guangzhou Area. There was a negative correlation between the need for family members to accompany, the experience of 5.12 earthquake and scores on the Overall health. The scores of male patients on Overall health were higher than that of female patients.

Key words: Quality of life, Hemodialysis, Multi-center study