中国血液净化 ›› 2015, Vol. 14 ›› Issue (10): 622-625.doi: 10.3969/j.issn.1671-4091.2015.10.00

• 透析心理学 • 上一篇    下一篇

女性血液透析患者焦虑、抑郁状态及对生活质量影响的研究

王云燕,封蕾,毛静,黄龙,汪静美,李云姝,黄群   

  1. 重庆,第三军医大学大坪医院血液净化中心
  • 收稿日期:2015-05-11 修回日期:2015-07-23 出版日期:2015-10-12 发布日期:2015-10-12
  • 通讯作者: 王云燕 382499300@qq.com E-mail:382499300@qq.com
  • 基金资助:

    “十二五”国家科技支撑计划项目(编号:2011BAI10B08)

The effect of anxiety and depression on quality of life in female patients with maintenance hemodialysis

  • Received:2015-05-11 Revised:2015-07-23 Online:2015-10-12 Published:2015-10-12

摘要: 目的探讨女性维持性血液透析(maintenance Hemodialysis,MHD)患者焦虑和抑郁发生率及其对生活质量的影响,为有效防治焦虑和抑郁奠定基础。方法对134 例女性MHD 患者应用焦虑自评量表(SAS)、抑郁自评量表(SDS)和生活质量评定简表(SF-36)对焦虑、抑郁以及生活质量进行评估。结果134 例女性MHD 患者的SAS 和SDS 的平均得分分别为43.45±9.23 和48.34±11.65,焦虑发生率为13.43%,抑郁症发生率为23.88%,在透析3~5 年中发生率最高。焦虑女性患者的生活质量评估显著低于非焦虑女性患者[躯体功能(PF),P=0.006;由躯体问题所造成的角色限制(RP),P<0.001; 躯体不适(BP)P=0.001;健康总体自评(GHP),P=0.009;活力(VT),P=0.001;情感角色(REP),P=0.008;心理健康(MH),P<0.001]。抑郁女性患者的生活质量显著低于非抑郁女性患者[躯体功能(PF),P=0.012; 躯体不适(BP)P=
0.041;健康总体自评(GHP),P=0.001;社会能力(SF)P=0.006;情感角色(REP),P=0.022;心理健康(MH),P=0.018]。结论女性MHD 患者焦虑、抑郁发生率较高,尤其是透析时间较长的患者更为明显。焦虑、抑郁对女性患者的生活质量有显著负面影响,甚至引发严重不良事件,因此,防治MHD 患者的焦虑、抑郁非常必要。

关键词: 血液透析, 焦虑, 抑郁, 生活质量

Abstract: Objective The maintenance hemodialysis (MHD) patients have a higher incidence of anxiety and depression, which are more severe in female patients and affect quality of life, dialysis, and prognosis of the disease. Here we explored the occurrence of anxiety and depression in female MHD patients and their
effects on quality of life, in order to effectively prevent and treat anxiety and depression. Methods Self-rating anxiety scale (SAS), self-rating depression scale (SDS), and short form 36 questionnaire (SF-36) were applied to psychological analysis of anxiety, depression and quality of life in 134 female patients on MHD. Results The mean scores of SAS and SDS in female MHD patients were 43.45±9.23 and 48.34±11.65, respectively. The incidence was 13.43% for anxiety (SAS score ≥50) and was 23.88% for depression (SDS score ≥ 50), with the highest incidence in patients on MHD for 3~5 years. The scores of SF-36 were obviously lower in female MHD patients with anxiety than in those without anxiety (P<0.05), except the social skills score of SF-36. Also, the scores of SF-36 were obviously lower in female MHD patients with depression than those without depression (P<0.05), except the role and vitality scores of SF-36. Conclusion There is a higher prevalence of anxiety and depression symptoms in female MHD patients, especially those with longer MHD duration. The symptoms of anxiety and depression have negative impact on quality of life even leading to seriously adverse events. Therefore, it is necessary to prevent and manage anxiety and depression in female MHD patients to improve their quality of life.

Key words: hemodialysis, anxiety, depression, quality of life