中国血液净化

›› 2003, Vol. 2 ›› Issue (1): 14-16.

• 论著 • 上一篇    下一篇

人体电阻率测定血液透析患者干体重在临床中的应用

姜 枫 薄玉红 王世相 毕增 衤其   

  1. 100020 北京，首都医科大学附属北京朝阳医院肾内科(姜 枫)，泌尿科(王世相，薄玉红)100730 北京，中国协和医科大学北京协和医院肾内科(毕增衤其)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2003-01-19 发布日期:2003-01-19

  • Received:1900-01-01 Revised:1900-01-01 Online:2003-01-19 Published:2003-01-19

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摘要： 【摘要】目的 干体重的测定对于准确评价透析患者的水负荷，预防水负荷过多所致的合并症具有重要意义。目前对于干体重的测定仍没有一种时效性强，准确性好，简单易行的方法。我们应用自行设计安装的人体生物电阻率测量系统对反映人体单位体积组织中的细胞外液容量的参数电阻率ρ作为干体重的指标进行了研究。本文为研究的部分结果。方法 应用电阻率测量系统分别测定正常人和血液透析患者血液透析前及结束时的下肢电阻率ρ，并动态观察电阻率ρ的变化。结果 同性别正常人不同年龄组之间电阻率ρ无明显差别，不同性别间正常人电阻率ρ有显著差别，男性明显低于女性；血液透析前患者电阻率ρ较正常人明显下降；有明显水负荷过多症状的患者经多次透析后，其透析结束时的电阻率ρ已达到正常范围，并且临床症状消失。结论 电阻率ρ能较准确地评价血液透析患者的干体重。

关键词: 生物电阻率ρ, 干体重, 血液透析

Abstract: 【Abstract】Objective To evaluate the dry weight is very important for management of hemodialysis patients, and for prevention of the symptoms due to body fluid over load. But now there is no kind of accurate, fast and simple method to measure the dry weight. We set up a bioelectrical resistivity measurement system (BRMS) and to study the bioelectrical resistivity as an indicator for dry weight in hemodialysis patients. Here is part of results in this study. Methods We measured the bioelectrical resistivity by our BRMS in control normal persons, and hemodialysis patients before and after dialysis procession. We also observed the dynamic changes of bioelectrical resistivity in hemodialysis patients. Results There was no significant difference among groups divided by age; but the bioelectrical resistivity was significantly lower in man than in woman. The bioelectrical resistivity measured before dialysis procession in hemodialysis patients was significantly lower than in normal control ones. The bioelectrical resistivity in patients with symptoms of body fluid over load became normal after several dialysis processions, and the symptoms released. Conclusion Bioelectrical resistivity can be used as an indicator to evaluate the dry weight in hemodialysis patients.

Key words: Dry weight, Hemodialysis