中国血液净化

中国血液净化 ›› 2016, Vol. 15 ›› Issue (12): 669-673.doi: 10.3969/j.issn.1671-4091.2016.12.005

• 临床研究 • 上一篇    下一篇

透析前阶段慢性肾脏疾病患者的生活质量的影响因素分析

赵平萍,蔡明玉   

  1. 第三军医大学大坪医院肾内科
  • 收稿日期:2016-05-24 修回日期:2016-10-26 出版日期:2016-12-12 发布日期:2016-12-05
  • 通讯作者: 蔡明玉 ss13816@sina.com E-mail:ss13816@sina.com

Analysis of the influencing factors on quality of life in patients with chronic kidney disease before dialysis

  • Received:2016-05-24 Revised:2016-10-26 Online:2016-12-12 Published:2016-12-05

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摘要： 目的 研究家庭收入、性别、年龄、血红蛋白和疾病分期等因素对透析前阶段慢性肾脏疾病患者生活质量的影响。方法对150 例透析前阶段慢性肾脏疾病患者和175 例健康对照人群应用生活质量评定简表(the MOS 36-item short form health survey,SF-36)对生活质量进行评估，并采集临床相关数据和实验室检查。结果男性透析前慢性肾脏病(chronic kidney disease,CKD)患者生活质量评分的生理功能(t=2.121,P=0.017)、生理职能(t=2.321,P=0.041)、躯体疼痛(t=2.412,P=0.025)和心理健康领域(t=2.121,P=0.017)得分明显高于女性患者。年龄≤47 岁的CKD 患者在生活质量评分中的生理功能方面优于年龄＞47 岁患者(t=2.891, P=0.015)，社会功能方面评分低于年龄＞47 岁患者(t=1.981,P =0.021)。血红蛋白≤90g/L 的CKD 患者在社会功能领域得分明显降低(F=1.432,P=0.015)。CKD4 期患者生理职能(F =3.121,P =0.004)、躯体疼痛(F =1.781,P =0.045)、活力(F=1.456,P =0.034)、社会功能领域(F =2.651,P =0.021)得分显著低于CKD1-3 期患者。家庭收入低于2 倍最低标准的患者生活质量显著降低，尤其在生理职能(F =3.213,P=0.001)、社会功能(F=2.231,P=0.013)、情感职能(F =3.657,P=0.001)、心理健康(F=2.476, P= 0.012)领域方面。结论性别、年龄、血红蛋白、家庭收入和CKD 分期是影响CKD 患者透析前阶段生活质量的重要因素，对于临床早期评估和干预CKD 患者生活质量具有重要的参考价值。

关键词: 生活质量, 影响因素, 慢性肾脏疾病

Abstract: Objective To investigate the effect of family income, gender, age, hemoglobin and disease stage on quality of life in patients with chronic kidney disease (CKD) before dialysis. Methods The quality of life of 150 CKD patients before dialysis in our hospital was evaluated by using the MOS 36- Item Short Form Health Survey (SF-36). Clinical data and laboratory test results were collected. Results The quality of life scores of physiological function (t=2.121, P=0.017), physiological performance (t=2. 321, P=0.041), bodily pain (t=2.412, P=0.025) and mental health (t=2.121, P=0.017) were significantly higher in male pre-dialysis CKD patients than in the female patients. Age ≤47 years patients had higher physiological function scores (t=2.891, P=0.015) and lower social function scores (t=1.981, P=0.021) than age ＞47 patients. Patients with hemoglobin ≤90g/L had lower scores in the field of social function (F=1.432, P=0.015). Stage 4 CKD patients had lower scores of physiological function (F=3.121, P=0.004), bodily pain (F=1.781, P=0.045), vitality (F=1.456, P=0.034) and social function (F=2.651, P=0.021) than stage 1~3 CKD patients. The quality of life decreased significantly in patients with family income less than 2 times of the minimum standard, especially in physiological function (F=3.213, P=0.001), social function (F=2.231, P=0.013), emotional function (F=3.657, P=0.001), and mental health (F=2.476, P=0.012). Conclusion Family income, gender, age, hemoglobin and disease stage are the critical factors influencing quality of life in CKD patients before dialysis. These factors have important values for early assessment and intervention of the quality of life in CKD patients.

Key words: quality of life, influencing factor, chronic kidney disease