中国血液净化

›› 2003, Vol. 2 ›› Issue (2): 79-81.

• 论著 • 上一篇    下一篇

慢性肾衰竭透析前患者促红细胞生成素的应用

杨 沐 刁秀竹 任 伟 柴树人   

  1. 230001 合肥，安徽省立医院肾内科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2003-02-19 发布日期:2003-02-19

  • Received:1900-01-01 Revised:1900-01-01 Online:2003-02-19 Published:2003-02-19

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摘要： 【摘要】目的 探讨rHuEPO治疗慢性肾衰竭透析前患者贫血的安全和可靠性。方法 采用随机前后自身对照的研究方法，给予46例慢性肾衰竭透析前贫血患者rHuEPO皮下注射，3000u/次，2次/周，观察疗程12周。结果 46例治疗患者显效26例，显效率56.5%，有效18例占39.1%，无效2例占4.3%,总有效率95.6% 。治疗前后肝、肾功能，血电解质改变无明显差异（P>0.05）。结论 rHuEPO治疗慢性肾衰竭透析前贫血患者疗效可靠、安全，不会使肾功能恶化，主要不良反应为高血压。

关键词: 促红细胞生长素, 贫血, 早期治疗, 慢性肾衰竭

Abstract: 【Abstract】Objective To determine the effectiveness and safety of rHuEPO madein chronic renal failure predialysis patient. Method using random, oneself contrasted method. 46 cases chronic renal failure predialysis patients received rHuEPO subcutaneouly,two times per week. The duration of rHuEPO therapy was 12weeks. Results Remarkable improvement rate of patient was 56.5%(26/46). Significant improvement rate of patient was 39.1%(18/46). No effectiveness rate of patient was 4.3%(2/46). Conclusions In our study, the treatment of chronic renal anemia predialysispatinent with rHuEPO was effectiveness and safety. rHuEPO related side effects was hypertension in 7(15.2%) patient.

Key words: Anemia, Early treatment, Chronic failure