关键词: 经皮腔内血管成形术, 人工血管动静脉内瘘, 早期血栓, 尿激酶

Abstract: 【Abstract】Objective To assess the safety and effectiveness of thrombolysis using urokinase combined with percutaneous transluminal angioplasty in the treatment of acute thrombosis in arteriovenous graft (AVG). Methods The clinical data of 20 patients with acute thrombosis in AVG and treated during the period from January 2017 to December 2018 were retrospectively analyzed. The diagnosis of acute thrombosis in AVG was confirmed by vascular ultrasound examination in all patients. After thrombolysis using urokinase, a syringe was used to repeatedly aspirate the thrombosis via the vascular sheath until no further thrombi could be aspirated, and angioplasty was then performed at the stenosis site as required. Technical success rate, complications and patency rate were analyzed. Results Technical success was achieved in all 20 cases (100 %). One case had hematoma at the puncture site, and the other cases had no complications. Primary patency rates were 100%, 87.5% and 75.0% after 3, 6, and 12 months, respectively. The secondary patency rates were 100%, 100% and 95%, respectively. Conclusions Thrombolysis using urokinase combined with percutaneous transluminal angioplasty in the treatment of acute thrombosis in AVG is safe and effective.

Key words: Percutaneous transluminal angioplasty, Arteriovenous graft, Acute thrombosis, Urokinase