中国血液净化

中国血液净化 ›› 2023, Vol. 22 ›› Issue (03): 161-163.doi: 10.3969/j.issn.1671-4091.2023.03.001

• 专题 •    下一篇

长效红细胞生成素的研究和应用进展

刘爱春   韦 洮   

  1. 100044 北京，1北京大学人民医院肾内科
  • 收稿日期:2023-01-04 修回日期:2023-01-08 出版日期:2023-03-12 发布日期:2023-03-03
  • 通讯作者: 韦洮 E-mail:weitao63@163.com

Research and Application Progress of Long acting Erythropoietin

LIU Ai-chun, WEI Tao   

  1. Department of Nephrology, Peking University People’s Hospital, Beijing 100044, China
  • Received:2023-01-04 Revised:2023-01-08 Online:2023-03-12 Published:2023-03-03
  • Contact: 100044 北京，1北京大学人民医院肾内科 E-mail:weitao63@163.com

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摘要： 我国有巨大的肾性贫血及肿瘤放化疗贫血患病人群。长效红细胞生成素(erythropoietin,EPO)具有半衰期长、生物活性高等优势，能降低给药频率和剂量，提高患者依从性、改善贫血治疗效果。本文就长效EPO的设计方案、优势及应用前景进行综述，旨在为促进长效EPO在国内广泛应用提供理论依据。

关键词: 贫血, 长效红细胞生成素, 优势

Abstract: China has a large number of patients with renal anemia and tumor anemia after radiotherapy and chemotherapy. Long acting erythropoietin (EPO) has the advantages of long half-life and high biological activity. It can reduce the frequency and dose of administration, improve patient compliance and improve the effect of anemia treatment. This paper summarizes the design scheme, advantages and application prospects of long-acting EPO in order to provide a theoretical basis for promoting the wide application of long-acting EPO in China.

Key words: Anemia, Long acting erythropoietin, Advantage

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