中国血液净化

中国血液净化 ›› 2023, Vol. 22 ›› Issue (10): 754-758.doi: 10.3969/j.issn.1671-4091.2023.10.008

• 临床研究 • 上一篇    下一篇

横断面调查超声测量视神经鞘直径在维持性血液透析患者中的分布情况

罗慧嫦    宋 利    尹 燕    全梓林    崔冬梅    赵立艳    陈  诚   

  1. 523110 东莞，1东莞东华医院肾内科
    510080 广州，2南方医科大学附属广东省人民医院(广东省医学科学院)肾内科
  • 收稿日期:2023-03-20 修回日期:2023-08-09 出版日期:2023-10-12 发布日期:2023-09-28
  • 通讯作者: 宋利 E-mail:songli@gdph.org.cn
  • 基金资助:
    广东省医学科学技术研究基金项目(A2021260)； 广州市科技计划项目(202102080292)

Cross-sectional survey of the distribution of optic nerve sheath diameter by ultrasound measurement in patients on maintenance hemodialysis

LUO Hui-chang, SONG Li, YIN Yan, QUAN Zi-lin, CUI Dong-mei, ZHAO Li-yan, CHEN Cheng   

  1. Department of Nephrology, Dongguan Tungwah Hospital, Dongguan 523110, China; 2Department of Nephrology, Guangdong Provincial People's Hospital, Southern Medical University (Guangdong Academy of Medical Sciences), Guangzhou 510080, China; 3Department of Nephrology, Peking University Shenzhen Hospital, Shenzhen 518034, China
  • Received:2023-03-20 Revised:2023-08-09 Online:2023-10-12 Published:2023-09-28
  • Contact: 510080 广州，2南方医科大学附属广东省人民医院(广东省医学科学院)肾内科 E-mail:songli@gdph.org.cn

PDF

64

摘要： 目的 通过对维持性血液透析(maintenance hemodialysis,MHD)患者横断面调查，应用超声测量其视神经鞘直径(optic nerve sheath diameter,ONSD)的数值分布情况。方法  选取2022年9月—10月的MHD患者，由同一检查者采用B型超声分别测量双眼球后3 mm处ONSD，每侧眼球均测量纵切面直径和横切面直径，将2次ONSD平均值作为该眼ONSD。 结果  共纳入206例患者，平均年龄(60.2±14.3)岁，平均透析时间62.5(26.0,113.0)月。其中女性166例(80.6%)，合并糖尿病71例(34.5%)，合并冠心病40例(19.4%)。MHD患者中男性ONSD平均直径高于女性(t=3.180,P=0.002)；男性患者左眼ONSD平均直径高于女性(t=-3.399,P=0.001)；与非糖尿病患者比较，糖尿病MHD患者左眼和右眼ONSD平均直径均显著增大，差异有统计学意义(t=-3.824,P＜0.001)；与非冠心病患者比较，冠心病MHD患者左眼和右眼ONSD平均直径差异均不显著(t=-1.064,P=0.289)。 结论 MHD患者ONSD分布与性别和是否合并糖尿病显著相关。临床中需关注男性、糖尿病患者左眼ONSD。

关键词: 超声测量, 视神经鞘直径, 血液透析, 颅内压

Abstract: Objectives  This is a cross-sectional survey to observe the distribution of optic nerve sheath diameter (ONSD) by ultrasound measurement in maintenance hemodialysis (MHD) patients.  Method  The MHD patients treated in the period from September to October 2022 were recruited. Ultrasound examination of both eyes was performed by one examiner. The ONSD of an eye was measured from the longitudinal and transverse eye sections 3mm after the bulb, and the two values were then averaged.  Results  A total of 206 MHD patients were enrolled, with the mean age of 60.2±14.3 years, the mean dialysis age of 62.5 (26.0～113.0) months, and 80.6% female patients (166 cases). Diabetic nephropathy was found in 71 cases (34.5%), and coronary heart disease was found in 40 cases (19.4%). The average ONSD was higher in males than in females (t=3.180, P=0.002). The average ONSD of left eyes was greater in males than in females (t=-3.399, P=0.001). The average ONSD of both eyes increased significantly in MHD patients with diabetes, as compared with those without diabetes (t=-3.824, P＜0.001). In contrast, the average ONSD of both eyes had no differences between the MHD patients with and without coronary heart disease (t=-1.064, P=0.289).  Conclusion  The distribution of ONSD is closely related to gender and the diabetic nephropathy in MHD patients. Clinically, the left side ONSD is significantly higher than that of right side in male patients with diabetic nephropathy. 

Key words: Ultrasound measurement, Optic nerve sheath diameter, Hemodialysis, Intracranial pressure

中图分类号: