中国血液净化

中国血液净化 ›› 2024, Vol. 23 ›› Issue (11): 839-843.doi: 10.3969/j.issn.1671-4091.2024.11.008

• 综述 • 上一篇    下一篇

吸附型体外生命支持技术临床应用研究进展

刘  欢    周金花   

  1. 272002 济宁，济宁市第一人民医院1急诊内科 2呼吸与危重症医学科
  • 收稿日期:2024-05-11 修回日期:2024-08-20 出版日期:2024-11-12 发布日期:2024-11-12
  • 通讯作者: 周金花 E-mail:duomi150701@163.com

Research advances in the clinical application of adsorption-based extracorporeal life support technology

LIU Huan, ZHOU Jin-hua   

  1. Department of Emergency Internal Medicine and 2Respiratory and Critical Care Medicine, Jining No.1 People's Hospital, Jining 272000, China
  • Received:2024-05-11 Revised:2024-08-20 Online:2024-11-12 Published:2024-11-12
  • Contact: 272002 济宁，济宁市第一人民医院 2呼吸与危重症医学科 E-mail:duomi150701@163.com

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摘要： 体外生命支持技术的进步为重症疾病治疗带来了新的选择。体外膜肺氧合(extracorporeal membrane oxygenation，ECMO)作为一种体外生命支持技术，有效提高了患者的存活率。然而，ECMO也面临一些挑战，例如炎症因子风暴引发的器官损伤等。为了克服这些问题，吸附型体外生命支持技术(extracorporeal life support with adsorption，ECLSA)应运而生。ECLSA综合了血液灌流和体外生命支持技术，通过去除炎性介质等有害成分，改善炎症反应，提高患者的存活率。ECLSA在急危重症疾病治疗中巨大的潜力。本文将对ECLSA在临床应用方面的进展进行综述。

关键词: 体外生命支持技术, 体外膜肺氧合, 血液灌流, 吸附型体外生命支持技术

Abstract: The progresses in extracorporeal life support technology have brought new options for the treatment of critical illnesses. The extracorporeal life support technology of extracorporeal membrane oxygenation (ECMO) has significantly increased survival rate of the patients. However, ECMO may also have problems, such as organ damage caused by the inflammatory cytokine storm. The presence of extracorporeal life support with adsorption technology (ECLSA) may overcome these problems. ECLSA combines blood perfusion and extracorporeal life support technology to remove harmful substances such as inflammatory mediators, thus improving inflammation response and enhancing survival rate of the patients. ECLSA shows great potential in the treatment of critical illnesses. This article provides an overview of the progresses in the clinical application of ECLSA.

Key words: Extracorporeal life support, Extracorporeal membrane oxygenation, Hemoperfusion, Extracorporeal life support with adsorption

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