中国血液净化 ›› 2025, Vol. 24 ›› Issue (05): 406-409.doi: 10.3969/j.issn.1671-4091.2025.05.010

• 综述 • 上一篇    

慢性肾脏病患者并发脑血管病的研究进展

赵鹏鸣 马思远 王晓玲   

  1. 730030 兰州,1兰州大学第二医院肾病内科
    730030 兰州,2兰州大学第二临床医学院
  • 收稿日期:2024-12-16 修回日期:2025-01-27 出版日期:2025-05-12 发布日期:2025-05-12
  • 通讯作者: 王晓玲 E-mail:1509867671@qq.com
  • 基金资助:
    兰州大学第二医院萃英学子科研培育计划(CYXZ2021-43)

Research progress in cerebral vascular disease in patients with chronic kidney disease

ZHAO Peng-ming, MA Si-yuan, WANG Xiao-ling   

  1. Department of Nephrology, Lanzhou University Second Hospital, Lanzhou 730030, China; 2Second Clinical Collage of Medicine, Lanzhou University, Lanzhou 730030, China
  • Received:2024-12-16 Revised:2025-01-27 Online:2025-05-12 Published:2025-05-12
  • Contact: 730030 兰州,2兰州大学第二医院肾病内科 E-mail:1509867671@qq.com

摘要: 慢性肾脏病(chronic kidney disease,CKD)与各类脑血管病关系密切,可能是由于它们有着共同的血管损伤危险因素,如高血压和糖尿病等。但是肾脏特异性危险因素,如尿毒症毒素、内皮功能障碍、矿物质和骨代谢异常等也被认为是CKD患者发生脑血管病的重要原因。本文就CKD并发脑血管病的类型和危险因素进行综述,以期减少脑血管病的发生,改善患者预后。

关键词: 慢性肾脏病, 脑血管病, 危险因素

Abstract: Chronic kidney disease (CKD) is frequently associated with a variety of cerebral vascular diseases including ischemic and hemorrhagic stroke, and small vessel disease. Conventional vascular risk factors such as hypertension and diabetes mellitus account for many of the cerebral vascular diseases in CKD patients, and renal-specific risk factors such as uremic toxin, endothelial dysfunction and abnormal calcium and phosphate metabolism also play important roles in the pathogenesis of the diseases. In this paper we introduce the types and risk factors of cerebral vascular diseases in CKD patients, in order to prevent the occurrence and to improve the prognosis of cerebral vascular diseases in the patients.

Key words: Chronic kidney disease, Cerebral vascular disease, Risk factor

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