中国血液净化

›› 2006, Vol. 5 ›› Issue (1): 13-15.

• 论著 • 上一篇    下一篇

复用透析器杀菌剂清除方法临床研究

范文奎 陈建英 梁艳影   

  1. 528000 佛山, 广东省佛山市第二人民医院血液净化中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2006-01-12 发布日期:2006-01-12

  • Received:1900-01-01 Revised:1900-01-01 Online:2006-01-12 Published:2006-01-12

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摘要： 目的 探讨合理实用的操作方法以达到复用透析器理想的杀菌剂残余量。方法 选择广东省佛山市第二人民医院血液净化中心长期血液透析患者47例随机分组，应用不同方法对透析器进行杀菌剂清洗，应用Renalin残余测试条检测透析器内残余的Renalin浓度，记录结果，观察患者临床表现。结果 应用生理盐水1 000ml冲洗透析器及管路，循环10min，可以使复用透析器残留Renalin浓度＜3mg/L，达到标准要求。但在聚砜膜高通量透析器残留Renalin浓度2mg/L时，仍有37.5%患者发生发热反应。聚砜膜材料高通量透析清洗杀菌剂较普通透析器困难，要采用生理盐水1000ml冲洗，循环15min的方法。结论 聚砜膜普通透析器(F6)清除杀菌剂应用生理盐水1000ml冲管,循环10min，经济安全有效；聚砜膜高通量透析器(F60S)要采用生理盐水1000ml冲洗,循环15min的方法,残留Renalin浓度需要≤1mg/L。

关键词: 透析器, 复用, 杀菌剂, 残余量

Abstract: Objective To investigate the reasonable way of germicide removal in the reusing dialyzers. Methods Patients enrolled were divided into different groups randomly. Different methods were used to rinse the reusing dialyzers to remove germicide. Renalin residual test strips were used to examine the renalin residual density. Results were rewrdedand clinical symptoms were observed. Results After rinsing the reusing dialyzers with Normal saline (NS) 1000ml for 10 minutes in singlepass fashion.The renalin residual density was lower than 3mg/L.Though the renalin residual of polysulfone high-flux dialyzer was lower than 2mg/L, 37.5% patients got fever. So 1000ml NS and 15 minutes were needed to rinse polysulfone high-flux dialyzer. Conclusion The way of rinsing NS 1000ml and circulating in a single-pass fashion for 10 minutes is effective in polysulfone dialyzer (F6). The way of rinsing NS 1000ml and circulating in a single-pass fashion for 15 minutes is effective in polysulfone high-flux dialyzer (F60S). The renalin residual density must be ≤1mg/L.

Key words: Reuse, Germicide, Residue

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