关键词: 腹膜透析, 水负荷, 生物电阻抗, 细胞内液, 细胞外液

Abstract:

Objective To investigate the fluid status of CAPD patients by bioimpedance analysis and to study the reasons of fluid overload. Methods Thirty-six CAPD patients were included in this study. Multifrequency BIA was performed using the Xitron BIS4200 device in all patients.The body weight,extracellular water(ECW),total body water (TBW), blood pressure,urine volume and ultrafiltrate volume were measured once every month.ECW were normalized by patients’ body surface area(BSA). Results In the first 6 months on dialysis, all the parameters that relate to fluid status including body weight、ECW、normalized ECW (nECW)、TBW increased, Whereas no significant difference was found in 24h ultrafiltration、24h urine and 24h total fluid removal ( P>0.05). Daily energy intake also increased significantly during the six-month follow-up. Systolic blood pressure was high before dialysis, but decreased after dialysis. Conclusion Our results suggested that fluid volume increased in most patients in the early stages of CAPD. The main reason was most probably excessive fluid and salt intake with the relief of uremia symptoms after dialysis.The increase in body weight in the early stages should not simply be considered as an improvement of nutritional status. This indicates the importance of salt and water restriction in CAPD patient even at the early stage of dialysis. 

Key words: Bioimpedance analysis, Fluid status 