中国血液净化

中国血液净化 ›› 2014, Vol. 13 ›› Issue (03): 143-145.doi: 10.3969/j.issn.1671-4091.2014.03.005

• 临床研究 • 上一篇    下一篇

维持性血液透析患者甲状旁腺超声筛查的临床意义

刘凤菊1,勇强1,程虹2,卞维静2   

  1. 首都医科大学附属北京安贞医院1 超声诊断科 2 肾内科
  • 收稿日期:2013-11-04 修回日期:2013-09-11 出版日期:2014-03-12 发布日期:2014-03-12
  • 通讯作者: 勇强 cfp99@163.com E-mail:cfp99@163.com

The clinical significance of parathyroid ultrasound screening in hemodialysis patients

  • Received:2013-11-04 Revised:2013-09-11 Online:2014-03-12 Published:2014-03-12

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摘要： 目的 探讨维持性血液透析（maintenance hemodialysis,MHD）患者实施甲状旁腺（parathyroid，PT）超声检查的临床意义；方法 收集MHD治疗1年以上患者的一般资料和相关实验室检查，根据全段甲状旁腺激素（intact parathyroid hormone,iPTH）水平分为A组（≥600pg/ml）和B组（<600pg/ml）实施PT超声检查。结果 有73例患者入选，其中A组55例，B组18例。A组PT超声检出率90.9%（50/55），B组PT超声检出率33.3%（6/18）,差异有统计学意义（P<0.001）；A、B两组间PT总体积存在显著性差异（t=4.171, P=0.021），单因素分析显示，iPTH水平与PT体积呈正相关（γ＝0.543,P=0.039）。结论 iPHT水平高于600pg/ml的MHD患者，高度提示存在PT增生的可能。

关键词: 维持性血液透析, 超声检查, 继发性甲状旁腺功能亢进

Abstract: Objective To investigate maintenance hemodialysis （MHD）for patients with parathyroid (PT) ultrasound clinical significance; Methods Collection MHD patients over one year of therapy and general information related laboratory examination, according to iPTH levels divided into group A (≥ 600pg/ml) and group B (<600pg/ml) implementation PT ultrasound. Results 73 patients were enrolled, including 55 cases of group A, B group 18 cases. Ultrasound PT detection rate: A group of 90.9% (50/55), B group of 33.3% (6/18), there was a significant difference between the two groups (P <0.001), PT total volume of significant differences also exit（t=4.171, P=0.021）. Univariate analysis showed that iPTH levels were positively correlated with PT volume (γ = 0.543, P = 0.039). Conclusion iPHT levels above 600pg/ml of MHD patients is highly suggestive of the possible presence of PT hyperplasia.

Key words: Maintenance hemodialysis, Ultrasonography, Secondary hyperparathyroidism