中国血液净化

中国血液净化 ›› 2014, Vol. 13 ›› Issue (07): 489-492.doi: 10.3969/j.issn.1671-4091.2014.07.002

• 临床研究 • 上一篇    下一篇

身高标化细胞外液在评估CAPD患者容量负荷及心肌重构中的价值

许义1,李琳1,卢国元1,汪小华2,居莉3,周莉3,庞建红4   

  1. 1苏州大学附属第一医院肾内科  2苏州大学护理学院  3 苏州大学附属第一医院营养科  4  苏州市盛泽医院
  • 收稿日期:2013-12-17 修回日期:2014-05-15 出版日期:2014-07-12 发布日期:2014-07-12
  • 通讯作者: 卢国元 sdfyylgy@163.com E-mail:xucy8327@126.com
  • 基金资助:

    苏州市科技计划项目(编号：SYS201310)

The value of normalized extracellular fluid volume by body height in the estimation of volume overload and ventricular remodeling in patients with continuous ambulatory peritoneal dialysis

  • Received:2013-12-17 Revised:2014-05-15 Online:2014-07-12 Published:2014-07-12

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摘要： 【摘要】 目的 探讨身高标化细胞外液（ECW∕h）在评估CAPD患者容量负荷及心室重构中的价值。方法 收集CAPD患者人体成分分析、心脏超声等资料。分析ECW∕h与心脏容量负荷及心室重构的相关性；不同ECW∕h组患者心脏容量负荷及心室重构的差异。结果 相关分析显示，CAPD患者ECW∕h与心脏容量负荷指标LVEDD及LAD呈正相关（r =0.507，0.492， p＜0.001）；与心室重构指标LVPWT、LVM、 IVST及LVMI呈正相关（r =0.463，0.581，0.403，0.404，p ＜0.001）。ECW∕h＞9.04 L∕m 组患者心脏容量负荷指标LVEDD及LAD显著高于ECW∕h＜9.04L∕m组患者（p ＜0.01）；ECW∕h＞9.04 L∕m 组患者心室重构指标IVM、IVST、LVPWT及LVMI显著高于ECW∕h＜9.04L∕m组（ p＜0.05）结论 ECW∕h在评估CAPD患者容量负荷及心室重构中有一定的临床价值。

关键词: 身高标化细胞外液, CAPD, 容量负荷, 心室重构

Abstract: Objective To explore the value of normalized extracellular fluid volume by body height (ECW/h) in the estimation of volume overload and ventricular remodeling in patients with continuous ambulatory peritoneal dialysis (CAPD). Methods Data about body composition and echocardiography were collected and used to analyze the correlation of ECWh with volume overload and ventricular remodeling. We also analyzed the differences of volume overload and ventricular remodeling in patients with ECW/h ＞9.04 L/m and those with ECW/h＜9.04L/m. Results Pearson’s analysis showed that ECWh was positively correla-ted with the volume load parameters of LVEDD and LAD (r=0.507 and 0.492, respectively; P＜0.001) and the ventricular remodeling parameters of LVPWT, LVM, IVST and LVMI (r =0.463, 0.581, 0.403 and 0.404, respectively; P＜0.001. Volume overload and ventricular remodeling indicators including LVEDD, LAD, LVPWT, LVM, IVST, and LVMI were higher in patients with ECW/h＞9.04 L/m than in those with ECW/h＜ 9.04L/m. Conclusion ECW/h is valuable in the clinical evaluation of volume overload and ventricular remodeling in CAPD patients.

Key words:  Normalization of ECW volume, Continuous ambulatory peritoneal dialysis, Volu-me overload, Ventricular remodeling