中国血液净化

中国血液净化 ›› 2015, Vol. 14 ›› Issue (04): 216-218.doi: 10.3969/j.issn.1671-4091.2015.04.008

• 临床研究 • 上一篇    下一篇

超声极速成像技术评价维持性血液透析患者颈动脉脉搏波传导速度的临床研究

张蕾1,勇强2,程虹2,卞维静2,王明月1,张依然1   

  1. 1. 首都医科大学附属北京安贞医院，北京市心肺血管疾病研究所综合超声科
    2. 首都医科大学附属北京安贞医院肾内科
  • 收稿日期:2014-11-21 修回日期:2015-02-05 出版日期:2015-04-12 发布日期:2015-04-20
  • 通讯作者: 勇强 cfp99@163.com E-mail:cfp99@163.com

Clinical investigation on carotid arterial pulse wave velocity measured by UltraFast imaging in maintenance hemodialysis patients

  • Received:2014-11-21 Revised:2015-02-05 Online:2015-04-12 Published:2015-04-20

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摘要： 目的  探讨应用超声极速成像技术(Ultrafast imaging，UltraFast™)定量评价维持性血液透析(Maintenance hemodialysis，MHD)患者颈动脉脉搏波传导速度(Pulse wave velocity，PWV)的临床应用价值。方法选取35 例MHD 患者和28 例正常对照组进行常规颈动脉超声检测，二维灰阶超声观察斑块情况，根据斑块有无将MHD 患者分为有斑块组和无斑块组。应用超声极速成像技术测量颈总动脉PWV，包括收缩期起始时BS 值及收缩期结束时ES 值。结果MHD 组与正常组PWV 比较，BS 值和ES 值差异均具有明显统计学意义(P 均＜0.05)。MHD 患者有斑块组和无斑块组比较，BS 值和ES 值差异均无明显统计学意义(P 均＞0.05)。结论超声极速成像技术安全、简便、无创、无辐射、快速，能够自动、精确检测颈动脉PWV，有望成为MHD 患者动脉硬化程度定量评价的影像学新方法。

关键词: 超声检查, 维持性血液透析, 颈动脉, 脉搏波传导速度, 极速成像技术

Abstract: Objective To assess the application value of Ultrafast imaging (UltraFast) for quantitative evaluation of carotid arterial pulse wave velocity (PWV) in maintenance hemodialysis (MHD) patients. Methods Routine carotid ultrasonography and UltraFast were performed in 35 MHD patients and 28 normal controls. The 35 MHD patients were classified into carotid arterial plaque (CAP) group or non-carotid arterial plaque (non-CAP) group by two dimensional gray scale features. Carotid arterial PWV was measured by UltraFast, including beginning of systolic (BS) value and end of systolic (ES) value. Results BS and ES values of carotid arterial PWV were significantly different between MHD patients and normal controls (P<0.05). However, BS and ES values were statistically indifferent between CAP group and non-CAP group (P>0.05). Conclusion UltraFast is a safe, convenient, fast, noninvasive, and non- radioactive imaging technique by which carotid arterial PWV can be automatically and accurately assayed. BS and ES values may be the new imaging indicators to quantitatively assess the carotid arterial stiffness in MHD patients.

Key words: Ultrasonography, Maintenance hemodialysis, Carotid, Pulse wave velocity, Ultrafast imaging