中国血液净化 ›› 2015, Vol. 14 ›› Issue (11): 658-661.doi: 10.3969/j.issn.1671-4091.2015.11.05

• 临床研究 • 上一篇    下一篇

血液透析患者血镁水平及相关营养状况分析

金咏菊,雷娟,王颖,檀敏,甘良英,赵新菊,左力   

  1. 北京大学人民医院肾内科
  • 收稿日期:2015-05-18 修回日期:2015-09-16 出版日期:2015-11-12 发布日期:2015-11-12
  • 通讯作者: 赵新菊 silverbirch-me@163.com E-mail:silverbirch-me@163.com

Serum magnesium level and its correlation with nutritional status in maintenance hemodialysis patients

  • Received:2015-05-18 Revised:2015-09-16 Online:2015-11-12 Published:2015-11-12

摘要: 【摘要】目的调查单个透析中心维持性血液透析(HD)患者血镁水平的现状,并比较不同血镁水平的
HD 患者的营养状况。方法选择北京大学人民医院血液透析室慢性维持性血液透析患者,收集患者
性别、年龄、身高、干体质量、原发病、透析龄、有无残余肾功能(RRF)等资料,计算体质量指数(BMI),采用
主观整体评估法(SGA)评估患者的营养状态;检测透析前血白蛋白、血镁水平。计算血镁异常发生率,根
据血镁水平将患者分组,比较不同组别患者的人口统计学及营养指标之间有无差异。结果共116 例
HD 患者纳入研究,其中男性69 例,女性47 例,男女比例为1.5:1;患者的平均年龄为(57.8±14.8)岁。血
镁平均值为(1.18±0.14)mmol/L,其中22 例患者血镁正常,94 例患者血镁升高,无低镁血症患者。高镁
血症发生比例为81.0%。相对于血镁正常的患者,高镁血症组患者年龄较轻[(63.91±13.26)mmol/L
vs.(56.37±14.86)mmol/L]、白蛋白水平更高[(38.67±3.04)g/L vs.(40.04±2.36)g/L],差异有显著
性;BMI 更大(22.64±3.17 vs. 24.02±4.32)、SGA 评分发生营养不良比例更低(13.6% vs. 5.3%),但没
有达到统计学差异。2 组患者性别构成、透析龄、原发病为糖尿病的比例以及有RRF 比例等指标之间差异
无显著性。结论HD 患者高镁血症发生率较高,发生高镁血症的患者通常年龄较轻、白蛋白水平等营
养指标更好。

关键词: 慢性肾脏病, 维持性血液透析, 高镁血症, 营养状况

Abstract: 【Abstract】Objective To investigate serum magnesium level in maintenance hemodialysis (MHD) patients
in a single HD center and to compare the serum magnesium (Mg) level with patients’nutritional status.
Methods MHD patients with stable clinical conditions in our hemodialysis center were enrolled in this
study. Demographic data, primary cause of the end stage renal disease, dialysis vintage, residual renal function
were recorded. Body mass index, subjective global assessment (SGA) score, pre- dialytic serum album
and Mg were obtained. Demographic data and nutritional markers were compared with the patients with different
serum Mg levels. Results A total of 116 patents (69 males and 47 females; males: females=1.5:1) with
the average age of 57.8±14.8 years were recruited for this study. The average serum Mg concentration was
1.18±0.14 mmol/L. Ninety- four patients (81.0%) had hypermagnesemia, 22 patients were in normal range,
and no patients had hypomagnesemia. Hypermagnesemia patients were younger with higher albumin level, as
compared with the patients having normal serum Mg. There were no statistical differences in gender, SGA
score, BMI, dialysis vintage, primary cause and residual renal function between patients with normal serum
Mg and those with hypermagnesemia. Conclusions Hypermagnesemia is prevalent in MHD patients. Patients
with hypermagnesemia are younger with better nutritional status.

Key words: chronic kidney disease, maintenance hemodialysis, hypermagnesemia, nutritional status