关键词: 肺动脉高压, 血液透析, 发病机制, 治疗

Abstract: Pulmonary arterial hypertension (PAH) is a chronic and progressive disease leading to right heart failure and death if untreated. It is a common abnormality in patients with dialysis-dependent chronic kidney disease, especially those having arteriovenous fistula. With the increase of chronic kidney disease patients, the prevalence of severe PAH and the mortality of cardiac diseases are significantly increasing. Several factors cause the development and progression of PAH. Clinically, PAH should be identified and treated earlier to mitigate the susceptible factors and to prevent the development of PAH.

Key words: Pulmonary arterial hypertension (PAH), Hemodialysis, Pathogenesis, Therapy