中国血液净化 ›› 2019, Vol. 18 ›› Issue (05): 328-331.doi: 10.3969/j.issn.1671-4091.2019.05.011

• 综述 • 上一篇    下一篇

肺动脉高压在慢性肾脏病中的研究进展

蔡蕊莲1,席春生1   

  1. 1. 中国人民解放军联勤保障部队第940医院肾内科
  • 收稿日期:2018-10-29 修回日期:2018-12-30 出版日期:2019-05-12 发布日期:2019-05-15
  • 通讯作者: 席春生 chunshxi@sina.com E-mail:chunshxi@sina.com

Research progresses in chronic kidney disease patients complicated with pulmonary hypertension

  • Received:2018-10-29 Revised:2018-12-30 Online:2019-05-12 Published:2019-05-15

摘要: 【摘要】肺动脉高压是以肺动脉压和肺血管阻力升高为特征的进行性疾病,最终导致右心功能衰竭,是慢性肾脏病患者的常见并发症。合并肺动脉高压的慢性肾脏病患者住院和死亡风险增加,是长期生存的重要预测指标。肺动脉高压在慢性肾脏病中的发病机制复杂,目前仍不十分清楚。临床上应早期识别并给予积极治疗。本文就慢性肾脏病患者肺动脉高压的研究进展作一综述。

关键词: 肺动脉高压, 慢性肾脏病, 危险因素, 治疗

Abstract: 【Abstract】Pulmonary hypertension is a progressive disease characterized by elevated blood pressure and vascular resistance in pulmonary arteries finally leading to right heart failure. It is a common complication in chronic kidney disease (CKD) patients. CKD patients with pulmonary hypertension have higher risk of hospitalization and death. Therefore, pulmonary hypertension is a unfavorable predictor for survival in CKD patients. The pathogenesis of pulmonary hypertension in CKD patients is complicated and remains elusive. Early identification and active treatment are clinically essential. This article reviews the research progresses in pulmonary hypertension in CKD patients.

Key words: pulmonary hypertension, chronic kidney disease, risk factor, treatment