中国血液净化

中国血液净化 ›› 2019, Vol. 18 ›› Issue (08): 556-559.doi: 10.3969/j.issn.1671-4091.2019.08.012

• 综述 • 上一篇    下一篇

慢性肾脏病合并妊娠最新研究进展

刘爱春1,燕宇1,左力1   

  1. 1. 北京大学人民医院 肾内科
  • 收稿日期:2019-06-06 修回日期:2019-06-13 出版日期:2019-08-12 发布日期:2019-08-15
  • 通讯作者: 燕宇 yanmail1004@163.com E-mail:yanmail1004@163.com

Chronic kidney disease women complicated with pregnancy

  1. 1Department of Nephrology, Peking University People’s Hospital, Beijing 100044, China
  • Received:2019-06-06 Revised:2019-06-13 Online:2019-08-12 Published:2019-08-15

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摘要： 【摘要】随着慢性肾脏病(chronic kidney disease，CKD)发病率不断增加，CKD 合并妊娠的人数也越来越多。CKD 合并妊娠时，既存肾脏病可能对妊娠及胎儿产生不良影响，同时妊娠也会加重CKD 的进展。妊娠与CKD 的关系包括妊娠可能导致CKD 的恶化、进展，CKD 也可能增加各类妊娠相关并发症。如何评估CKD 患者的妊娠时机，并对妊娠过程进行监测和管理是临床医生和患者共同关心的问题。本文总结了近年来有关CKD 合并妊娠的最新进展，并详细介绍了几种常见肾脏病(如IgA 肾病、狼疮性肾炎、糖尿病肾病)合并妊娠的研究结果，同时总结了肾脏病相关药物在妊娠期间的调整原则。

关键词: 慢性肾脏病, 妊娠, IgA肾病, 狼疮性肾炎, 糖尿病肾病

Abstract:

【Abstract】The number of pregnant women with various degrees of renal dysfunction becomes increasing, as the incidence of chronic kidney disease (CKD) is going up worldwide. CKD and pregnancy are mutually affected, in which the pregnancy and fetus are adversely affected by the renal dysfunction, and the processes of CKD may deteriorate due to the pregnancy. Both clinicians and the patients are concerned about the appropriate time for pregnancy and how to monitor and manage the pregnancy in CKD women. In this review, we review the recent progresses in CKD women with pregnancy, introduce the outcomes of pregnancies and fetuses in women with several common nephropathies such as IgA nephrology, lupus nephritis and diabetic nephropathy, and summarize the protocols to adjust CKD-related drugs during pregnancy.

Key words: Chronic kidney disease, Pregnancy, IgA nephropathy, Lupus nephritis, Diabetic nephropathy

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