中国血液净化

中国血液净化 ›› 2019, Vol. 18 ›› Issue (10): 697-700.doi: 10.3969/j.issn.1671-4091.2019.10.010

• 血管通路 • 上一篇    下一篇

负压条件下不同血液透析管路的流速比较

马颖慧1,王艳2,尹佳宁3,刘静1.4   

  1. 1. 首都医科大学附属北京佑安医院血液净化中心
    2. 北京大学第一医院肾内科
    3. 首都医科大学附属北京朝阳医院血液净化科
    4. 首都医科大学肾病学系
  • 收稿日期:2019-03-29 修回日期:2019-06-28 出版日期:2019-10-12 发布日期:2019-09-27
  • 通讯作者: 刘静13661265853@163.com E-mail:13661265853@163.com

Comparison of flow rate in different bloodlines in dialyzers under negative pressure

  1. 1Blood Purification Center, Youan Hospital, Capital Medical University,Beijing 100069, China;  2Renal Division, Peking University First Hospital, Beijing 100034, China;  3Department of Blood Purification, Beijing Chao-Yang Hospital, Capital Medical University, Beijing 100020, China; 4Institute of Nephrology, Capital Medical University, Beijing 100069, China
  • Received:2019-03-29 Revised:2019-06-28 Online:2019-10-12 Published:2019-09-27

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摘要：

【摘要】目的   比较泵前存在负压的条件下不同血液透析管路的实际流速。方法   选取4种不同品牌的管路A、B、C、D，分别以200ml/min和300ml/min的设定流速运转5min，测量不同泵前负压条件下各管路的实际流速。结果①血泵设定流速相同时，泵前负压越大实际流速越低；②设定转速为200ml/min 时，- 120mmHg(1mmHg=0.133kpa)条件下不同品牌管路的实际流速无统计学差异(F =2.095，P =0.120)，-100mmHg 和-200mmHg 条件下不同品牌管路的实际流速存在统计学差异(F =4.157, 11.128，P=0.014, ＜0.001）；③设定转速为300ml/min 时, -100mmHg 和-200mmHg 条件下不同品牌管路的实际流速存在统计学差异(F=6.861, 18.748, P=0.001，＜0.001)。结论泵前负压影响体外循环的实际流速，且不同品牌的管路在相同负压条件下实际流速有一定差异，可进一步研究该差异对临床治疗效果的影响。

关键词: 血液透析, 负压, 管路, 流速

Abstract:

【Abstract】Objective To compare the flow rate in bloodlines of different dialyzer under negative pressure. Methods In this paper, bloodlines A, B, C and D in 4 brands of dialyzers were selected. Each bloodline ran at the speed of 200 ml/min and 300 ml/min for 5 minutes, and the actual flow rate in each bloodline was measured under different pre-pump negative pressures. Results ①The greater the pre-pump negative pressure was, the lower the actual flow rate became under the same rate setting. ②There was no statistical difference in actual flow rate in different brands of bloodlines under the set conditions of flow rate 200 ml/min and the pressure -20mmHg (F=2.095, P=0.120). In contrast, there was statistical difference in actual flow rate in
the bloodlines under the pressure of -100mmHg and -200mmHg (F=4.157 and 11.128 respectively; P=0.014 and ＜0.001 respectively). ③There was statistical difference in actual flow rate in different brands of bloodlines under the rate of 300ml/min and the pressure of -100mmHg and -200mmHg (F=6.861 and 18.748 respectively; P=0.001 and ＜0.001 respectively). Conclusion The negative pre-pump pressure affected the actual flow rate of extracorporeal circulation. The difference of actual flow rate existed among bloodlines of different brands under the same negative pressure conditions. Therefore, the clinical effect of these differences should be further studied.

Key words: Hemodialysis, Negative pressure, Bloodline, Flow rate

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