中国血液净化

中国血液净化 ›› 2019, Vol. 18 ›› Issue (11): 801-804.doi: 10.3969/j.issn.1671-4091.2019.11.019

• 血液净化中心管理 • 上一篇    下一篇

2 种不同类型透析机的对比研究

赵小淋1,任琴琴1,朱晗玉1,马志芳1   

  1. 1解放军总医院第一医学中心肾脏病科
  • 收稿日期:2018-07-30 修回日期:2019-08-22 出版日期:2019-11-12 发布日期:2019-10-28
  • 通讯作者: 马志芳mazhifang301@126.com E-mail:mazhifang301@126.com
  • 基金资助:
    国家自然科学基金（61971441）：基于多模态深度学习的糖尿病肾病诊断方法研究；
    国家自然科学基金(61671479)：原发性IgA 肾病尿蛋白质组学数据库及无创诊断模型的建立；
    国家重点研发项目(2016YFC1305500)：2 型糖尿病肾病表观遗传改变及其调控机制研究

A comparative study of two different types of dialysis machines

  1. 1Department of Nephrology, First Medical Center of PLA General Hospital, Beijing 100853, China
  • Received:2018-07-30 Revised:2019-08-22 Online:2019-11-12 Published:2019-10-28
  • Contact: ma zhifang E-mail:mazhifang301@126.com

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摘要： 【摘要】目的对比中央透析液供给系统(central dialysis fluid delivery system，CDDS)与普通透析机2 种类型设备的透析液洁净度以及故障率，分析CDDS 透析设备的临床应用优势与不足。方法于2017 年8 月～2018 年3 月选择解放军总医院透析中心CDDS 透析机GC-110N 与贝朗德佳透析机各5 台，对比2 组透析机入口与出口处样本细菌、内毒素水平。回顾性分析解放军总医院2 类透析设备各18 台在2017 年3 月～2019 年3 月期间水路、电路以及其他故障的发生率。结果透析机入口采样点CDDS 组透析机细菌、内毒素水平均低于普通组透析机(t 值分别为11.215、6.468，P 值分别为＜0.001，＜0.001)。透析机出口采样点CDDS 组透析机细菌、内毒素水平均低于普通组透析机(t 值分别为9.154、5.490，P 值分别为＜0.001，＜0.001)。CDDS 组透析机水路、电路以及其他故障的总计发生率均低于普通组透析机, 差异有统计学意义(t=9.147，P=0.010)。结论CDDS 系统可提高透析液洁净度，降低透析设备故障率在临床应用中具有一定优势。

关键词: 多人用透析装置, CDDS 系统, 透析液洁净度

Abstract:

【Abstract】Objective To compare the cleanliness and failure rate between the dialysis machines with central dialysis fluid delivery (CDDS) system and the conventional dialysis machines, and to analyze the clinical application advantages of the dialysis machines with CDDS system. Methods From August 2017 to March 2018, the bacteria number and endotoxin level at the inlet and outlet sites were compared between the dialysis machines with CDDS system (5 sets) and the Berengdejia dialyzer (5 sets) in the PLA General Hospital Dialysis Center. A retrospective analysis was performed on the incidence of water, circuit and other faults occurred in the dialysis machines with CDDS system (18 sets) and the Berengdejia dialyzer (18 sets) during the period from March 2017 to March 2019. Results The bacteria number and endotoxin level at the inlet were lower in the dialysis machines with CDDS system than in the conventional dialysis machines (t=11.215 and 6.468 respectively; P＜0.001). The bacteria number and endotoxin level at the outlet were also lower in the dialysis machines with CDDS system than in the conventional dialysis machines (t=9.154 and 5.490 respectively; P＜0.001). The incidence of water, circuit and other faults were lower in the dialysis machines with CDDS system than in the conventional dialysis machines (t=9.147, P=0.010). Conclusion CDDS system can improve the cleanliness of dialysate and reduce the failure rate of dialysis machines during clinical applicati

Key words: Multi-purpose dialysis device, CDDS system, Dialysis fluid cleanliness

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