中国血液净化

中国血液净化 ›› 2024, Vol. 23 ›› Issue (06): 445-448.doi: 10.3969/j.issn.1671-4091.2024.06.010

• 综述 • 上一篇    下一篇

血液透析患者中必需微量元素的益处和风险

胡 睿     刘 岩    刘 云   

  1. 550004 贵阳，1贵州医科大学临床医学院
    510220 广州，2暨南大学附属广州红十字会医院肾内科 营养研究所
  • 收稿日期:2024-03-12 修回日期:2024-03-27 出版日期:2024-06-12 发布日期:2024-06-12
  • 通讯作者: 刘岩 E-mail:rabbityan127@163.com

The benefits and risks of essential trace elements in hemodialysis patients

HU Rui, LIU Yan, LIU Yun   

  1. Clinical Collage of Medicine, Guizhou Medical University, Guiy ang 550004, China; 2Department of Nephrology, Institute of Disease-Oriented Nutritional Research, Guangzhou Red Cross Hospital, Jinan University, Guangzhou 510220, China
  • Received:2024-03-12 Revised:2024-03-27 Online:2024-06-12 Published:2024-06-12
  • Contact: 550004 贵阳，1贵州医科大学临床医学院；510220 广州，2暨南大学附属广州红十字会医院肾内科营养研究所 E-mail:rabbityan127@163.com

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摘要： 肾脏是人体微量元素代谢的重要器官，对于终末期肾病(end-stage renal disease,ESRD)患者，因为食物摄入的减少、肠道吸收功能的改变、肾脏排泄功能的下降以及肾衰竭所致体内代谢的改变，会导致体内全血、血清或血浆微量元素发生改变。同时，由于透析清除和透析液水质量存在差异，对于接受血液透析(hemodialysis,HD)治疗的患者，在之前的基础上，体内微量元素更容易出现缺乏和过量的风险，并与HD患者的多种并发症以及住院、死亡风险相关。因此，对HD患者微量元素的研究具有重要的临床意义。

关键词: 慢性肾脏病, 血液透析, 微量元素

Abstract: Kidney is an important organ for metabolism of trace elements in human body. In end-stage renal disease (ESRD) patients, changes in trace element levels in whole blood, serum or plasma may occur due to reduced food intake, abnormal function of intestinal absorption, decreased renal excretion capacity, and metabolic alterations resulting from renal failure. Additionally, hemodialysis patients face an even greater risk of trace element deficiency or excess due to the differences in dialysis clearance and quality of dialysis water. The abnormal metabolism of trace elements is associated with risks of various complications, hospitalization and mortality among hemodialysis patients. Therefore, the study of trace elements in hemodialysis patients is of clinical importance. 

Key words: Chronic kidney disease, Trace element, Hemodialysis

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