中国血液净化

中国血液净化 ›› 2025, Vol. 24 ›› Issue (03): 177-180.doi: 10.3969/j.issn.1671-4091.2025.03.001

• 指南与共识 •    下一篇

《血液吸附清除肌红蛋白：横纹肌溶解血液吸附工作组共识报告》解读

周晓春    杨莹莹    张 凌    付 平   

  1. 610041 成都，四川大学华西医院1肾脏内科 2肾脏病研究所
    618300 德阳，3广汉市中医医院肾内科
  • 收稿日期:2024-09-11 修回日期:2024-11-21 出版日期:2025-03-12 发布日期:2025-03-12
  • 通讯作者: 杨莹莹 E-mail:yingyingyangsf@163.com
  • 基金资助:
    四川大学华西医院院内基金项目(ZYGD23015)

Interpretation of hemoadsorption to clear myoglobin: consensus report of HRTF

ZHOU Xiao-chun, YANG Ying-ying, ZHANG Ling, FU Ping   

  1. Department of Nephrology, 2Kidney Research Institute, West China Hospital of Sichuan University, Chengdu 610041, China; 3Department of Nephrology, Guanghan Hospital of Traditional Chinese Medicine, Deyang 610213, China
  • Received:2024-09-11 Revised:2024-11-21 Online:2025-03-12 Published:2025-03-12
  • Contact: 610041 成都，四川大学华西医院1肾脏内科 2肾脏病研究所 E-mail:yingyingyangsf@163.com
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摘要： 横纹肌溶解(rhabdomyolysis,RM)是一种多因素导致肌肉组织坏死后肌红蛋白(myoglobin, MB)、肌酸激酶(creatine kinase,CK)进入血液循环中的一种临床综合征。这些物质在体内的积累可导致严重的并发症，尤其是急性肾损伤(acute kidney injury,AKI)。血液吸附(hemoadsorption，HA)已被证实可以有效清除血液循环中的MB。2024年横纹肌溶解血液吸附工作组(consensus of the hemoadsorption in rhabdomyolysis task force，HRTF)制定了血液吸附清除肌红蛋白的国际共识。本文就该共识要点内容进行解读，供国内同行参考。

关键词: 血液吸附, 横纹肌溶解, 肌红蛋白, 共识

Abstract: Rhabdomyolysis (RM) is a syndrome in which multiple factors lead to the entry of myoglobin (MB) and creatine kinase (CK) into the circulation after necrosis of muscle tissue. Accumulation of these substances in the body can lead to serious complications, especially acute kidney injury (AKI). Hemoadsorption (HA) has been shown to be effective in removing MB from circulation. In 2024, the consensus of the hemoadsorption in rhabdomyolysis task force (HRTF), composed of international expert groups from six European countries, has formulated a global consensus on removing MB by HA (hereinafter referred to as consensus). This article interprets the key points of the consensus for the reference of domestic counterparts.

Key words: Hemoadsorption, Rhabdomyolysis, Myoglobin, Consensus

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