中国血液净化

中国血液净化 ›› 2025, Vol. 24 ›› Issue (03): 255-259.doi: 10.3969/j.issn.1671-4091.2025.03.019

• 护理研究 • 上一篇    下一篇

维持性血液透析患者口腔衰弱与肌少症关系的研究

梅 燕   刘安诺    窦俊凯   杨 亮   李雪晴   张欲雨   

  1. 230000 合肥，1安徽医科大学护理学院
    237000 六安，2六安市人民医院肾脏内科血液净化中心
  • 收稿日期:2024-07-29 修回日期:2024-12-29 出版日期:2025-03-12 发布日期:2025-03-12
  • 通讯作者: 刘安诺 E-mail:w971002y@sohu.com

The correlation between oral frailty and sarcopenia in maintenance hemodialysis patients

MEI Yan, LIU An-nuo, DOU Jun-kai, YANG Liang, LI Xue-qing, ZHANG Yu-yu   

  1. School of Nursing, Anhui Medical University, Hefei 230000, China; 2Blood Purification Center, Department of Nephrology, Lu’an People’s Hospital, Lu’an 237000, China
  • Received:2024-07-29 Revised:2024-12-29 Online:2025-03-12 Published:2025-03-12
  • Contact: 230000 合肥，1安徽医科大学护理学院 E-mail:w971002y@sohu.com

摘要： 目的 调查维持性血液透析患者口腔衰弱和肌少症的现状，并分析二者之间的关系。 方法 选取2023年8月─2024年2月六安市人民医院肾脏内科血液净化中心237例维持性血液透析患者进行横断面研究，采用一般资料调查表、口腔衰弱指数-8量表、简化的营养食欲调查量表及人体成分分析仪进行数据采集。 结果 维持性血液透析患者口腔衰弱的发生率为40.9%，肌少症的发生率为34.6%。Logistic回归分析结果显示：肌少症(OR=3.858，95% CI:1.453～10.242,P=0.007)是维持性血液透析患者口腔衰弱的影响因素。肌少症的评估参数，包括握力(OR=0.904，95% CI:0.849～0.963,P=0.002)与步速(OR=0.015，95% CI:0.003～0.083,P＜0.001)均是口腔衰弱的影响因素。结论 维持性血液透析患者口腔衰弱和肌少症的发病率高，肌少症是其影响因素，临床医护人员应多关注维持性血液透析患者的口腔衰弱和肌少症情况。

关键词: 维持性血液透析, 口腔衰弱, 肌少症, 关系

Abstract: Objective  To study the current situation of oral frailty and sarcopenia and their correlation in patients undergoing maintenance hemodialysis (MHD).  Methods  A total of 237 MHD patients were selected for a cross-sectional study. General information questionnaire, oral frailty index-8, simplified nutritional appetite questionnaire and a body composition analyzer were used for this study.  Results  The incidence of oral frailty was 40.9%, and the incidence of sarcopenia was 34.6% in the MHD patients. Logistic regression analysis showed that sarcopenia (OR=3.858, 95% CI: 1.453～10.242, P=0.007) was the main risk factor for oral frailty, and the parameters of sarcopenia, including grip strength (OR=0.904, 95% CI: 0.849～0.963, P=0.002), and gait speed (OR=0.015, 95% CI: 0.003～0.083, P＜0.001) were also risk factors for oral frailty in the MHD patients.  Conclusion  The incidence rates of oral frailty and sarcopenia are higher in MHD patients, and sarcopenia is the risk factor for oral frailty. Clinicians and nurses should pay attention to the presence of  oral frailty and sarcopenia in MHD patients.

Key words: Maintenance hemodialysis, Oral frailty, Sarcopenia, Correlation

中图分类号: