中国血液净化

›› 2002, Vol. 1 ›› Issue (12): 19-21.

• 论著 • 上一篇    下一篇

连续性肾脏替代疗法在重症肾综合征出血热少尿期的应用

刘拉羊 邓 红 赵 婕 李小燕   

  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2002-12-19 发布日期:2002-12-19

  • Received:1900-01-01 Revised:1900-01-01 Online:2002-12-19 Published:2002-12-19

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摘要： 【摘要】目的 评价和比较连续性肾脏替代疗法与血液透析在重症肾综合征出血热少尿期治疗中对预后的影响。方法 31例重症肾综合征出血热少尿期患者分为两组，采用CVVH治疗者11例为治疗组，血液透析治疗20例为对照组，两组性别、年龄及肾功能均匹配，分别观察两组患者的预后和并发症的发生情况。结果 两组在预后和并发症方面有明显差别，治疗组11例全部存活，仅一例合并感染。对照组出现并发症15例；主要为出血、感染、低血压、失衡综合征和二次肾功能衰竭，其中3例因二次肾功能衰竭而死亡。结论 连续性肾脏替代疗法较血液透析有更好的清除尿毒症毒素，纠正水、电解质、酸碱平衡失调及清除炎性介质的作用，可减少并发症。作为治疗重症肾综合征出血热少尿期的有效方法，可替代血液透析。

关键词: 连续性肾替代疗法, 肾综合征出血热, 血液透析

Abstract: 【Abstract】 Objective To evaluate and compare the different clinical outcome of patients with hemorrhagic fever with renal syndrome(HFRS) undergoing continous renal replacement therapy(CRRT) and hemadialysis(HD). Methods 31 patients with critical hemorrhagic fever with renal syndrome were divided into two groups, continuous venovenous hemafiltration(CVVH) of CRRT were performed in 11 patients as the treatment group .As the control group HD were used in other 20 patients. The age, sex and renal function between two groups were matching,their prognosis and the occurrence of complications were observed. Results There are satistically significant difference in prognosis and complications between two groups. 11 patients treated with CRRT in treatment group were all recovery. Only one case of patients in treatment group combineded with imfectious.There are 15 cases of complications include hemorrhage, hypotension,imbalance sydrome, relapse renal failure and infectious happened in control group and 3 patients died of complication. Conclusion The effects of CRRT was more obvious than HP in the clearance of uremia toxicity and the correction of the unequilibrium of water, electrolytes,acid and alkaline and may decrease the complication. As a more effective treatment method in critical HFRS ,CRRT can replace the HD.

Key words: Hemorrhagic fever with renal syndrome, Hemodialysis