中国血液净化

›› 2003, Vol. 2 ›› Issue (12): 662-664.

• 人工肝 • 上一篇    下一篇

人工肝支持系统治疗重症黄疸型肝炎的临床观察

王宝华 宋树芬 陈美珠   

  1. 266033 青岛，山东省青岛第六人民医院血液净化中心
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2003-12-19 发布日期:2003-12-19

  • Received:1900-01-01 Revised:1900-01-01 Online:2003-12-19 Published:2003-12-19

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摘要： 目的 探讨应用人工肝支持系统对(ALSS)黄疸型肝炎的临床疗效及安全性。方法 治疗组72 例共行人工肝治疗221次，平均3.2次，比较治疗前后临床表现。主要实验室检查指标及人工肝的不良反应。设同期住院病情相似的病例56例为对照组。结果 治疗组症状明显好转；血TBIL、ALT、AST、NH3、TBA、GGT明显下降，PTA、ALB升高；治愈好转率88.89%，不良反应率16.7%。对照组治愈好转率60.71%。治愈好转病例住院时间：治疗组（27.16±20.36）天，对照组（58.15±25.49）天，两组比较有显著差异。结论 ALSS为黄疸型肝炎患者提供了较为安全有效的治疗手段。

关键词: 人工肝支持系统, 黄疸型肝炎, 疗效

Abstract: Objective To investigate the clinical effects and safety of artificial liver support system (ALSS) in patients with jaundice hepatitis. Methods Seventy-two patients were treated with ALSS for 221 times, and 3.2 times on average. Compared the clinical manifestation, the main laboratory examination and the adverse reactions of the treatment. Fifty-six similar patients who were admitted to the hospital durtry the same time were as control. Results The patients undergoing artificial liver treatment showed significant improvements in clinical symptoms; TBIL, ALT, AST, NH3, TBA, and GGT reduced and PTA, ALB imcreased significantly. The incidence of adverse reaction was 16.7%, 88.89% of pationts in therapy group were cured or improved and 60.71% in the control group. The average duration of hospitalization:in (27.16±20.36) d treatment group, and (58.15±25.49)d normal control, there is a significant difference between the two groups. Conclusions ALSS can provide patients with comparatively secure and effective treatment for patients with jaundice hepatitis.

Key words: Jaundice hepatitis, Curative effect 