【Abstract】Objective To analyze the relationship between calcium and phosphate product and nutritional status in maintenance hemodialysis (MHD) patients. Methods A retrospective study was performed to assess calcium and phosphorus metabolism and nutritional status in 110 MHD patients in The First Hospital of Wuhan City from Jan. 2007 to Dec. 2007. Patients were assigned to group A (calcium and phosphate product ≤55mg/dl) or group B (calcium and phosphate product >55mg/dl). Comparison was made between the two groups. Results Higher levels of serum phosphate (P＜0.01), albumin, pre-dialysis BUN, total cholesterol and triglyceride (P<0.05) were found in group B, as compared with those of group A, whereas serum calcium, hemoglobin and iPTH had no differences between the two groups. Conclusion Elevated calcium and phosphorus product in MHD patients may result from the improvement of nutritional status and the increase of phosphate intake.