中国血液净化

›› 2004, Vol. 3 ›› Issue (8): 423-425.

• 论著 • 上一篇    下一篇

可调钠透析对血液透析患者相对血容量及心功能的影响

王松岩 苗里宁   

  1. 116011 大连，大连医科大学附属第一医院泌尿内科(王松岩)130041 长春，吉林大学第二医院肾病内科(苗里宁)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2004-08-12 发布日期:2004-08-12

  • Received:1900-01-01 Revised:1900-01-01 Online:2004-08-12 Published:2004-08-12

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摘要：

目的 探讨可调钠透析（PHD）对血液透析患者相对血容量（RBV）的影响，以及长期应用可调钠透析对心功能的影响。方法 选择30例规律血液透析患者，按常规血液透析模式(CHD)和可调钠透析模式（PHD）分为两组，观察两组血液透析患者相对血容量随时间的变化规律，实验开始及3个月后应用彩超检测心功能，比较两组的差异。结果 ①两组患者相对血容量随时间下降的变化在透析2小时后差异显著，PHD组相对血容量的减少明显低于CHD组，P<0.01，有统计学意义；② PHD组血液透析患者3个月后其反映心脏收缩功能的指标射血分数（EF），左室短轴缩短率（FS），峰值射血率（PER）明显增加，反映心脏舒张功能的指标心房充血分数（AFF）明显降低，P<0.01，有统计学意义。而CHD组三个月后EF，FS无明显变化，PER升高，AFF下降，P<0.05。说明长期可调钠透析更有助于改善血液透析患者的心功能。

关键词: 血液透析, 可调钠, 心功能

Abstract:

Objective This study is designed to observe the effects of sodium profile hemodialysis on the relative blood volume and cardiac function. Methods Thirty patients were selected and divided into two groups randomly: conventional hemodialysis (CHD) and profiled hemodialysis (PHD). Relative blood volume (RBV) were observed and recorded every 30 minutes. Cardiac function were tested in the beginning and at the end of the study. Results RBV in both groups decreased gradually, but the loss of RBV is lower in PHD group than in CHD group in two hours of hemodialysis, the difference is significant, P<0.01. Three months later in PHD group, the index of cardiac systolic function: ejection fraction(EF), fractional shortening(FS), peak ejection rate(PER) increased dramatically, the index of cardiac diastolic function artrial filtration fraction (AFF) decreased dramatically, P<0.01. In CHD group, EF, FS didn't change obviously, PER increased, AFF decreased three months later, P<0.05. From this we can see that long-term profiled hemodialysis is helpful to improve the cardiac function of the hemodialysis patients. Conclusion PHD can retain more relative blood volume (RBV) than CHD. A long-term PHD can improve CRF patients' cardiac systolic and diastolic function and is better than CHD. 

Key words: Sodium profile, Cardiac function 

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