中国血液净化

›› 2009, Vol. 8 ›› Issue (9): 490-491.

• 论著 • 上一篇    下一篇

闭式循环对血液透析相关的嗜酸粒细胞增多症的影响

韩东升 曹立云 王 芳 吕继成 左 力

  

  1. 北京大学第一医院肾内科
  • 收稿日期:2009-05-05 修回日期:1900-01-01 出版日期:2009-09-12 发布日期:2009-09-12

Effect of closed-rinse on hemodialysis related eosinophilia

HAN Dong-sheng, CAO Li-yun, WANG Fang, LV Ji-cheng, ZUO Li   

  1. Department of Nephrology, Peking University First Hospital, Beijing 100034, China
  • Received:2009-05-05 Revised:1900-01-01 Online:2009-09-12 Published:2009-09-12

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摘要：

【摘要】目的 探讨用闭式预冲循环的方法对血液透析相关的嗜酸粒细胞增多症的影响。方法 选择我院持续存在嗜酸粒细胞增多症的维持血液透析患者7名，全部患者排除其它引起嗜酸粒细胞增多的原因，应用闭式循环冲洗透析器及管路3个月，收集每月患者的静脉血，检查外周血嗜酸粒细胞计数及百分比，观察患者每次透析的临床表现及记录每月嗜酸粒细胞计数及百分比，比较嗜酸粒细胞的变化趋势。 结果 7名患者经闭式循环冲洗透析器及管路后，嗜酸粒细胞计数值的中位数由0.73降到0.48，百分比的中位数由13.0%降到5.6%，P＜0.05。结论 闭式预冲透析器及管路可能改善血液透析相关的嗜酸粒细胞增多症。

关键词: 嗜酸粒细胞增多症, 闭式预冲, 血液透析

Abstract:

【Abstract】 Objective To determine the effect of closed-rinse on hemodialysis related eosinophilia. Methods Seven patients on regular hemodialysis and with sustained hemodialysis related eosinophilia were enrolled in this study. We used closed-rinse to clean the dialyzers and tubes for 3 months. Peripheral eosinophil count and percentage, and clinical symptoms were observed every month. Results Eosinophil count and percentage decreased significantly (median count decreased from 0.73 to 0.48, median percentage from 13.0% to 5.6%, P＜0.05) after using the closed-rinse. Conclusion Closed-rinse to clean the dialyzers and tubes may reduce the presence of hemodialysis related eosinophilia.

Key words: Closed-rinse, Hemodialysis