中国血液净化

›› 2003, Vol. 2 ›› Issue (4): 180-182.

• 论著 • 上一篇    下一篇

尿毒症患者听力状况的临床研究

李松杨 林顺涨 赵德美   

  1. 200040 上海，上海市静安区中心医院肾内科(李松杨)200003 上海，第二军医大学长征医院耳鼻喉科(林顺涨)710003 西安，陕西省西安市中心医院肾内科(赵德美)
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2003-04-19 发布日期:2003-04-19

  • Received:1900-01-01 Revised:1900-01-01 Online:2003-04-19 Published:2003-04-19

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摘要： 目的 研究评价慢性肾功能不全尿毒症患者听力状况。方法 选择59例尿毒症患者，男37例， 女22例，年龄(39±10)岁。尿毒症病程(16±26)月，45例维持性血液透析已(14±26)月2例腹膜透析，11例药物治疗。59例中20例有不同程度耳鸣，听力下降感，突发性耳聋3例，余无症状。既往均无耳疾史，均行纯音电测听。结果 共有34例（55耳）出现语音频段或高频区听力损害，占总耳数47%，均为感应神经性耳聋。33耳语音频段听力受损，平均听力(37±18) dB；45耳高频区听力受损，平均听力(44±16)dB，虽然高频区听力损失较语音频段重，但无统计学差异（ P＞0.05），59例患者语音频段平均听力(21±14) dB，高频区(24±15)dB，正常对照组44例语音频段平均听力(14±3)dB，高频区(14±4)dB，经u检验 P均＜0.01，差异非常显著。结论 尿毒症患者既有临床又有亚临床听力受损，高频区听力损害可能是尿毒症患者听力损害的早期表现。

关键词: 尿毒症, 耳聋, 听力, 电测听

Abstract: Objective To evaluate the state of hearing in the patients of chronic renal failure. Methods 59 cases of uremic patients tested with pure tone audiometry.They are male in 37 cases and female in 22, average ages 39±10 years. The course of uremia is (16±26)M, 45 cases in continure hemodialysis, 2 cases in peritonealdialysis, 11 cases in received drugs therapy. 20/59 cases have symptoms of tinnitus, decrease hearing in different degree, 3 cases have suddenly deafness, the other no symptoms,all of them have no history of ear disease. Results 34 cases (55 ears) appeared hearing loss in the audio-frequency and high-frequency, were 47% in total ears, all of them were sensorineural deafness. 33 ears had audio-frequency hearing loss, (0.5-2 khz)average hearing (37±18)dB, 45 ears had high-frequency hearing loss (4-8 khz), average hearing (44±16)dB, although the degree in high frequency is severer than in audiofrequency, but no different between them (P>0.05). 59 cases average hearing in audio frequency is (21±14) dB, in high-frequency (24±15)dB, 44 cases normal control, the average hearing in audio-frequency is (14±3)dB, and high-frequency (14±4)dB. There is a significant different between the average hearing in uremic patients and normal control (P<0.01). Conclusion The uremic patients have hearing loss either clinical or subclinical. The high-frequency hearing loss maybe early stage sign in uremic patients.

Key words: Deafness, Hearing, Audiometry