关键词: 血液透析, 血容量, 低血压

Abstract: Objectives To study the efficacy of relative blood volume monitoring which biofeedback control the ultrafiltration rate in dialysis session for reducing the intradialysis complications. Methods Thirty dialysis patients were enrolled in the study from Dec. first 2000 to Dec. first 2004. During the 4 years, the patients were treated with common hemodialysis and BVM (blood volume monitoring) dialysis alternately, the total numbers of the dialytic sessions with episodes of hypotension or minor symptoms such as headache, muscular cramps, nausea, or abdominal pain were counted. The pre and post-dialytic blood pressure, the alteration of body weight were noted respectively. Results The 30 patients had undergone 6550 common dialysis sessions in the 4 years, in which 630 dialysis sessions had presented hypotension, 801 dialysis sessions had presented minor symptoms, and 6555 BVM dialysis sessions were undergone in the 4 years, in which 330 dialysis sessions had presented hypotension. Four hundred and ten dialysis sessions had presented minor symptoms.The rates of hypotension and minor episodes occurred in dialysis session were decreased significantly when using the BVM dialysis treatment (P<0.05) without over retention of body fluid. The alteration of body weight between the two kinds of dialysis presents no significant difference. Conclusions Relative blood volume monitoring which biofeedback-control the ultrafiltration speed in dialysis session can help to decrease the rate of episodes of intradialytic hypotension or minor symptoms such as headache, muscular cramps, nausea, or abdominal pain and can help to increase patient's tolerance to the blood dialysis. But BVM dialysis treatment could not prevent all the intradialytic hypotension and minor symptoms from occurring. The mechanism of the benefits of BVM dialysis and other methods for decreasing the rate of episodes of intradialytic complications is still awaiting further study. 

Key words: Blood volume, Hypotension