中国血液净化

›› 2005, Vol. 4 ›› Issue (3): 139-141.

• 论著 • 上一篇    下一篇

Kt/V标准差(δKt/V)作为慢性血液透析患者临床综合状况重要判断指标的探讨

韦 洮 张大伟 赵慧萍 赵青艺 檀 敏 蔡美顺 杨洪杰 于仲元
  

  1. 100044 北京，北京大学人民医院肾内科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2005-03-12 发布日期:2005-03-12

  • Received:1900-01-01 Revised:1900-01-01 Online:2005-03-12 Published:2005-03-12

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摘要： 目的 了解慢性血液透析患者Kt/V标准差(δKt/V)与血压、血清白蛋白浓度的关系，探讨Kt/V 标准差(δKt/V)作为血液透析充分性参数以及δKt/V在慢性血液透析患者综合临床状况分析中的指示性作用。方法 本研究选择慢性维持性血液透析患者80例测定血液透析开始 后2h收缩压、舒张压、平均动脉压，测定血液透析前血清白蛋白浓度、Kt/V，计算δKt/V，观察其与收缩压、舒张压、平均动脉压,血液透析前血清白蛋白浓度相关关系。结果 血液透析患者δKt/V与血清白蛋白浓度呈负相关(r=-0.690， P<0.05，有显著性差异)。透析开始后 2h收缩压、舒张压、平均动脉压高低呈正相关(r1=0.400, P<0.01; r2=0.255, P<0.05; r3=0.367; P<0.01)。结论 血液透析患者的血压控制与透析治疗条件的掌握密切相关，血液透析后患者血压的高低是血液透析治疗效果的重要指标之一，血清白蛋白亦是反映慢性肾衰竭患者营养状况的重要指标，其浓度与透析患者的生存质量密切相关，慢性血液透析患者 δKt/V范围是反映血液透析患者血液透析治疗质量的重要参数。δKt/V可作为透析患者综合临床状况分析的一项重要指标。

关键词: 维持血液透析, KT/V标准差, 血压, 血清白蛋白

Abstract:

Objective To understand the relationship between standard deviation of Kt/V（δKt/V） and the blood pressure、serum albumin concentration of chronic maintenance hemodialysis patients and to investigate the role of δKt/V in evaluating the general clinical conditions of the hemodialysis patients. Methods The blood pressure were observed 2 hs after the beginning of one hemodialysis session and δKt/V were calculated. The relationship of δKt/V and the systolic blood pressure (SBP) diastolic blood pressure (DBP) and mean blood pressure (MBP) were analyzed. Results There was a significant positive correlation between the SBP, DBp and MBp change and the range of δKt/V (r1=0.400, P<0.01; r2=0.255, P<0.05; r3=0.367; P<0.01 respectively). The blood pressure control closely depended on the quality of hemodialysis therapy. There was a significant negative correlation (r=-0.690，P<0.05) between δKt/V and the serum albumin concentration in chronic maintenance hemodialysis patients. Conclusion The δKt/V range of the chronic maintenance hemodialysis patients is a valuable index for the hemodialysis quality. δKt/V can be an important indicator for the evaluation of the general clinical conditions of the chronic maintenance hemodialysis patients.

Key words: Standard deviation of Kt/V（δKt/V）, Blood pressure, Serum albumin 

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