中国血液净化

中国血液净化 ›› 2026, Vol. 25 ›› Issue (05): 386-390,396.doi: 10.3969/j.issn.1671-4091.2026.05.005

• 临床研究 • 上一篇    下一篇

维持性血液透析患者家属心理状况对患者影响的研究

孙 超   王欣欣    陈 迪    石 颖   程 军    马迎春
  

  1. 100068 北京，首都医科大学康复医学院 中国康复研究中心北京博爱医院1肾内科 3计财处
    100068 北京，2中国康复科学所康复信息研究部
  • 收稿日期:2025-07-09 修回日期:2026-02-13 出版日期:2026-05-12 发布日期:2026-05-12
  • 通讯作者: 马迎春 E-mail:mych323@163.com
  • 基金资助:

A study on the impact of family members' psychological status on patients undergoing maintenance hemodialysis

SUN Chao，WANG Xin-xin，CHEN Di，SHI Ying，CHENG Jun，MA Ying-chun   

  1. Department of Nephrology，and 3Department of Finance, The School of Rehabilitation Medicine of Capital Medical University, China Rehabilitation Research Center/Beijing Boai Hospital，Beijing 100068, China; 2Department of Rehabilitation Information Research, Rehabilitation Information Research Department，China Rehabilitation Science Institute, Beijing 100068, China
  • Received:2025-07-09 Revised:2026-02-13 Online:2026-05-12 Published:2026-05-12
  • Contact: 100068 北京，首都医科大学康复医学院 中国康复研究中心北京博爱医院1肾内科 E-mail:mych323@163.com

摘要： 目的 探讨维持性血液透析(maintenance hemodialysis,MHD)患者家属心理状况对患者的影响。 方法 入组中国康复研究中心血液透析超过3个月的MHD患者及家属，评估二者心理状态、生活质量等指标的相关性。 结果 患者及其对应家属各入组140例，家属焦虑评分与患者焦虑评分呈正相关  (r=0.190，P=0.025)，与患者健康相关生活质量评分中的症状评分、肾脏病影响评分、肾脏病负担评分、躯体功能评分及心理状态评分呈负相关(r=-0.183、-0.208、-0.189、-0.216、-0.188，P=0.030、0.014、0.026、0.011、0.026)；家属抑郁评分与患者焦虑、抑郁评分呈正相关(r=0.192、0.359，P值分别为0.023、 ＜0.001)，与患者症状评分、肾脏病影响评分、心理状态评分呈负相关(r=-0.173、-0.215、      -0.185，P=0.041、0.011、0.029)；家属无焦虑(n=116)、无抑郁(n=53)时MHD患者的血β2微球蛋白较低(t=-2.364，-2.100，P=0.019、0.038)；家属无抑郁时MHD患者的血白蛋白水平较高(t=2.078，P=0.040)。 结论 家属的心理状态与患者焦虑、抑郁水平、生活质量及血β2微球蛋白水平、血白蛋白水平均相关。

关键词: 维持性血液透析, 家属, 焦虑, 抑郁

Abstract: Objective  To explore the influence of the psychological status of family members on patients undergoing maintenance hemodialysis (MHD).  Methods  MHD patients who had undergone hemodialysis for more than three months at the China Rehabilitation Research Center and their family members were enrolled. The correlation between their psychological status, quality of life, and other indicators was assessed.  Results  A total of 140 patients and their corresponding family members were enrolled. Family members' anxiety scores were positively correlated with patients' anxiety scores (r=0.190, P =0.025), and negatively correlated with patients' health-related quality of life subscores, including symptom score, kidney disease impact score, kidney disease burden score, physical function score, and psychological status score (r=−0.183,−0.208, −0.189, −0.216, −0.188; P=0.030, 0.014, 0.026, 0.011, 0.026). Family members' depression scores were positively correlated with patients' anxiety and depression scores (r=0.192, 0.359;P=0.023,<0.001,respectively), and negatively correlated with patients' symptom score, kidney disease impact score, and psychological status score (r =−0.173, −0.215, −0.185; P =0.041, 0.011, 0.029). When family members were free of anxiety (n=116) or depression (n=53), MHD patients had lower serum β2-microglobulin levels (t=−2.364, −2.100; P=0.019, 0.038). When family members were free of depression, MHD patients had higher serum albumin levels (t =2.078, P=0.040).  Conclusion  The psychological status of family members is correlated with patients' anxiety and depression levels, quality of life, serum β2-microglobulin levels, and serum albumin levels.

Key words: Maintenance hemodialysis ;Family members, Anxiety, Depression

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