中国血液净化 ›› 2020, Vol. 19 ›› Issue (11): 768-771.doi: 10.3969/j.issn.1671-4091.2020.11.012

• 综述 • 上一篇    下一篇

H 型高血压在慢性肾脏病中的研究进展

赵亚1,王俭勤1   

  1. 1兰州大学第二医院肾病内科
  • 收稿日期:2020-06-30 修回日期:2020-07-30 出版日期:2020-11-12 发布日期:2020-11-05
  • 通讯作者: 王俭勤 wangjianqin@medmail.com.cn E-mail:zhaoy2018@lzu.edu.cn
  • 基金资助:
    国家自然科学基金(81960142);国家自然科学基金(81560122);甘肃省陇原青年创新创业人才项目(2020RCXM127)

Research progress in H- type hypertension in chronic kidney disease

  1. 1Department of Nephrology, The Second Hospital of Lanzhou University, Lanzhou 730000, China
  • Received:2020-06-30 Revised:2020-07-30 Online:2020-11-12 Published:2020-11-05

摘要: 【摘要】慢性肾脏病的治疗面临巨大的困难和挑战,当前的治疗主要以干预危险因素为主。H 型高血压与慢性肾脏病患者肾功能的减退及心血管病并发症的发生有关。现就H 型高血压的定义、流行病学、与慢性肾脏病的关系以及导致其进展的机制进行综述,以提高临床医师对H 型高血压与慢性肾脏病关系的认识,协助临床治疗。

关键词: 慢性肾脏病, 高同型半胱氨酸血症, H 型高血压, 协同作用, 氧化应激, 炎症反应

Abstract: 【Abstract】Great difficulties and challenges are encountered in the treatment of chronic kidney disease, and the current treatment is mainly focused on the intervention of the risk factors. H-type hypertension is associated with renal insufficiency and cardiovascular complications in chronic kidney disease patients. This article reviews the definition, epidemiology, relationship between H-type hypertension and chronic kidney disease, and the mechanism that H-type hypertension leads to the progression of chronic kidney disease, in order to improve our understanding about the relationship between H-type hypertension and chronic kidney disease, which may be useful for clinical treatment of hypertension in chronic kidney disease patients.

Key words: Chronic kidney disease, Hyperhomocysteinemia, H-type hypertension, Synergistic effect, Oxidative stress, Inflammation

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